A critical makeover for pharmaceutical companies: Overcoming industry obstacles with a cross-functional strategy. PwC
A critical makeover for pharmaceutical companies: Overcoming industry obstacles with a cross-functional strategy. PwC report. Going all "cross-functional" or "breaking down silos"?
"Compounding the external obstacles, however, is the internal culture of most pharma companies. This is an industry...
Source: pwc.com
Change in clinical practice is slow even when it is obvious change should occur. Changing to a generic drug took 8 months
Change in clinical practice is slow even when it is obvious change should occur. Changing to a generic drug took 8 months and it was 18 months for adopting a guideline on UTI. "Substantial variation was observed in the speed with which individual NHS general practices responded to warranted changes...
Source: bmj.com
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’ style payment model to incentivise pharmaceutical companies to develop new drugs for resistant infections.
"The new trial will be led by the National Institute for...
Source: www.gov.uk
NHS to save 'hundreds of millions' in landmark drug ruling in England: Two drug companies were trying to stop doctors offering
NHS to save 'hundreds of millions' in landmark drug ruling in England: Two drug companies were trying to stop doctors offering a cheaper eye treatment.
Source: bbc.com
Is pharma rolling in cash or on the brink of a long-term decline? - Healthcare Economist "Although successful drugs often
Is pharma rolling in cash or on the brink of a long-term decline? - Healthcare Economist "Although successful drugs often are expensive, most drugs fail. Thus, while the returns from a blockbuster drug are large, returns from a companies’ entire portfolio may be very modest. Additionally, finding...
Source: healthcare-economist.com
Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound,
Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound, injected in to CSF and designed to reduce the production of all forms of the huntingtin (HTT) protein, which in its mutated variant (mHTT) is responsible for Huntington's Disease....
Source: reuters.com
Insulin-sensitising drugs for women with a diagnosis of polycystic ovary syndrome and subfertility | Cochrane
Insulin-sensitising drugs for women with a diagnosis of polycystic ovary syndrome and subfertility | Cochrane
Source: cochrane.org
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis: Objective To compare the efficacy, safety, and cost effectiveness of direct acting oral anticoagulants (DOACs) for patients with atrial fibrillation.
Design...
Source: bmj.com
Thyroid drug to stay on the NHS: The decision on liothyronine was part of a wider prescribing review by NHS England.
Thyroid drug to stay on the NHS: The decision on liothyronine was part of a wider prescribing review by NHS England.
Source: bbc.co.uk
How one country persuaded teens to give up drink and drugs: Iceland used to have a big teenage drinking, smoking and drug
How one country persuaded teens to give up drink and drugs: Iceland used to have a big teenage drinking, smoking and drug problem. Now it doesn't.
Source: bbc.co.uk
Police raid Merck pharmaceutical plant amid mysterious drug crisis: Is something wrong with hormone therapy or are patients
Police raid Merck pharmaceutical plant amid mysterious drug crisis: Is something wrong with hormone therapy or are patients over-reacting?
Source: arstechnica.com
Prescription drug 'floods' black market: A BBC investigation has seen first-hand of the devastating impact of the prescription
Prescription drug 'floods' black market: A BBC investigation has seen first-hand of the devastating impact of the prescription drug pregabalin which has 'flooded' the black market.
Source: bbc.co.uk
Baby boomers' drink and drug misuse needs urgent action, warn experts: By 2020, the number of over-50s receiving treatment
Baby boomers' drink and drug misuse needs urgent action, warn experts: By 2020, the number of over-50s receiving treatment for substance misuse problems is expected to double in Europe and treble in the US, say researchers
Source: theguardian.com
Treatment for hypertension in adults aged 18 to 59 years | Cochrane "Antihypertensive drugs used to treat predominantly
Treatment for hypertension in adults aged 18 to 59 years | Cochrane "Antihypertensive drugs used to treat predominantly healthy adults aged 18 to 59 years with mild to moderate primary hypertension have a small absolute effect to reduce cardiovascular mortality and morbidity primarily due to reduction...
Source: cochrane.org
Japanese fungus spreading in UK hospitals - BBC News: More than 200 patients have been infected, but none has died, Public
Japanese fungus spreading in UK hospitals - BBC News: More than 200 patients have been infected, but none has died, Public Health England confirms. "The first UK case emerged in 2013. Since then, infection rates have been going up - although it remains rare. Candida auris is proving hard to stop because...
Source: bbc.co.uk
Is Exenatide a Treatment for Parkinson’s Disease? Athauda, Dilan. Wyse, Richard. Brundin, Patrik. Foltynie, Thomas. Journal
Is Exenatide a Treatment for Parkinson’s Disease? Athauda, Dilan. Wyse, Richard. Brundin, Patrik. Foltynie, Thomas. Journal of Parkinson's Disease. "There is growing interest in the use of glucagon-like peptide-1
agonists as treatments for Parkinson’s disease following the recent
publication...
Source: iospress.com
Advice to "Complete the Course" of Most Antibiotics Seen as Unfounded: By Joe Elia Edited by Susan Sadoughi, MD The
Advice to "Complete the Course" of Most Antibiotics Seen as Unfounded: By Joe Elia
Edited by Susan Sadoughi, MD
The "deeply embedded" view that failing to complete a course of antibiotics will lead to drug resistance has no evidentiary basis, according to an analysis in The BMJ . … NEJM Journal...
Source: jwatch.org
Fake Malaria Meds Meet Their Match in a Handheld Spectrometer: Up to 35 percent of antimalarial drugs are useless. Engineers
Fake Malaria Meds Meet Their Match in a Handheld Spectrometer: Up to 35 percent of antimalarial drugs are useless. Engineers are combatting this counterfeit menace. "The new system uses near-infrared (NIR) spectrometry, directing a beam
of NIR light at a pill and recording how the light is absorbed....
Source: ieee.org
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults | Cochrane
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults | Cochrane
Source: cochrane.org
Cancer Drug Fund didn’t deliver value ‘to patients or society’: A fund that spent more than £1 billion on expensive
Cancer Drug Fund didn’t deliver value ‘to patients or society’: A fund that spent more than £1 billion on expensive new cancer drugs in England had little clinical benefit, a study of 29 medicines has concluded
Source: newscientist.com
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