Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
Collaborative Care Linked to Better Outcomes in Substance Use Disorders: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD
Patients with alcohol or opioid use disorder treated with a collaborative care model in primary care are twice as likely to receive evidence-based...
Source: jwatch.org
Continuous Glucose Monitoring May Improve Glucose Control in Type 2 Diabetes Requiring Insulin: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD
Among patients with type 2 diabetes, continuous glucose monitoring is associated with better glucose control, according...
Source: jwatch.org
Risky Alcohol Intake on the Rise — Especially in Women, Minorities, Seniors: By Kelly Young
Edited by Susan Sadoughi, MD
The prevalence of high-risk drinking and alcohol use disorder increased sharply over a decade, constituting a public health crisis, a JAMA Psychiatry study concludes.
Two surveys...
Source: jwatch.org
Canadians with Cystic Fibrosis Live Roughly 10 Years Longer Than Americans: By Kelly Young
Edited by Jaye Elizabeth Hefner, MD
Canadian patients with cystic fibrosis have a survival advantage over their U.S. counterparts, according to a study in the Annals of Internal Medicine . … NEJM Journal...
Source: jwatch.org
Climate Change Already Affecting Human Health: By Kelly Young
Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM
The Medical Society Consortium on Climate & Health, comprising 11 medical societies, is "sounding … NEJM Journal Watch.
Source: jwatch.org
WHO: 12 Bacteria Families Urgently Require New Antibiotics: By Kelly Young
Edited by David G. Fairchild, MD, MPH
The World Health Organization has listed 12 families of bacteria that "pose the greatest threat to human health" because of resistance to … NEJM Journal Watch.
Source: jwatch.org
No Long-Term Survival Benefit from Endovascular Repair of AAA Versus Open Repair: By Kelly Young
Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, FASAM
Endovascular repair of abdominal aortic aneurysm carries lower short-term but higher long-term mortality risks than open repair, according...
Source: jwatch.org
WHO Pushes for Taxes on Sugary Beverages: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM
The World Health Organization … NEJM Journal Watch.
Source: jwatch.org
First Suspected Female-to-Male Sexual Transmission of Zika Reported: By Kelly Young
Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH
The first case of female-to-male sexual transmission of the Zika virus has been documented in MMWR . Previously, only transmission from males to their partners...
Source: jwatch.org
Very Low Chance of Major Zika Spread Because of Olympics, WHO Says: By Kelly Young
Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, FASAM
The World Health Organization estimates that the Summer Olympics in Brazil will pose a very low risk for international transmission of the Zika...
Source: jwatch.org
Cost of Insulin Has Nearly Tripled: By Kelly Young
Edited by David G. Fairchild, MD, MPH
The price of insulin nearly tripled over the course of a decade, according to a JAMA research letter.
Researchers surveyed 28,000 … NEJM Journal Watch.
Source: jwatch.org
Societies Offer New Guidelines on Duration of Dual Antiplatelet Therapy: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM
The American Heart Association and the American College of Cardiology have released new guidelines on the appropriate duration of...
Source: jwatch.org
Lowering Blood Pressure Associated with Reductions in Cardiovascular Events, Meta-Analysis Finds: By Kelly Young
Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH
Reducing systolic blood pressure is associated with lower risk for cardiovascular events, suggests a meta-analysis in the Lancet...
Source: jwatch.org
Tylenol for Flu Symptoms Might Not Be Helpful: By Kelly Young
Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS
Acetaminophen may not be much help for influenza, according to … NEJM Journal Watch.
Source: jwatch.org
USPSTF Guidelines Recommend Ambulatory Blood Pressure Monitoring: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD
The U.S. Preventive Services Task Force recommends ambulatory blood pressure monitoring as the reference standard for confirming a diagnosis … NEJM...
Source: jwatch.org
Researchers Warn of Rare Injuries Observed with Epi-Pen Administration in Kids: By Kelly Young
Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS
Epinephrine autoinjectors have caused lacerations and embedded-needle injuries in children, although the adverse events are likely rare, according...
Source: jwatch.org