Discovery of a structural class of antibiotics with explainable deep learning.
One of the challenges with deep learning (neural networks) is that although they find patterns the reasoning disappears into an endless detail of numbers. In this paper the researchers built an 'explainable' AI to discover antibiotics instead of such a 'black box'. "The discovery of novel structural...
Source: nature.com
6 expert essays on the future of biotech
How will biotechnology transform our approach to human health? Scientists from the World Economic Forum's Global Future Council share key insights. World Economic Forum future of biotech DNA technology - genetic screening for disease, recombinant protein production, CAR T cells, gene therapy, organoid...
Source: weforum.org
Biopharma 2020: A landmark year and a reset for the future
Biopharma in 2020 has shown what it can achieve when it works at its best. How can the industry build on this renewed sense of purpose in the years ahead? McKinsey biopharma 2020 3 Overarching trends Operating under a spotlight - expectation of innovationNavigating protracted economic uncertainty -...
Source: mckinsey.com
5 failures of political leaders during a public health crisis
“There are five traps political leaders can fall into when it comes to a public health emergency: 1. delay and downplay; 2. fudge the science; 3. isolation from the international community; 4. absence; and 5. double standards.” Sophie Harman Professor of International Politics at Queen Mary University...
Source: qmul.ac.uk
France and Germany thrust into lockdown as second COVID-19 wave sweeps Europe: French President Emmanuel Macron and German
France and Germany thrust into lockdown as second COVID-19 wave sweeps Europe: French President Emmanuel Macron and German Chancellor Angela Merkel ordered their countries back into lockdown on Wednesday, as a massive second wave of coronavirus infections threatened to overwhelm Europe before the winter.
Source: reuters.com
The truth about the Second Wave
The truth about the Second Wave - uncancelled: We need to move away from binary certainties – the battle of the Professors of Hope vs the Doom mongers is not a helpful one. The truth is somewhere in between. It’s nuanced. Dr Matt Morgan, ICU Consultant in Cardiff, argues that we need to say "I don't...
Source: uncancelled.co.uk
Supporting migrants and refugees with posttraumatic stress disorder: development, pilot implementation, and pilot evaluation
Supporting migrants and refugees with posttraumatic stress disorder: development, pilot implementation, and pilot evaluation of a continuing interprofessional education for healthcare providers: Refugees and migrants face an increased risk of developing posttraumatic stress disorder (PTSD). Adequate...
Source: biomedcentral.com
Open source learning analytics
Stephen's Web ~ Learning Analytics beyond the LMS: Enabling Connected Learning via Open Source Analytics in ‘the wild’ ~ Stephen Downes "This excellent report (55 page PDF) will introduce you to the Connected Learning Analytics (CLA) toolkit." Overview of an approach to learning analytics.
Source: downes.ca
The new cultural norm: reasons why UK foundation doctors are choosing not to go straight into speciality training: The number
The new cultural norm: reasons why UK foundation doctors are choosing not to go straight into speciality training: The number of UK foundation doctors choosing to go straight into speciality training has fallen drastically over the last 10 years: We sought to explore and understand the reasons for...
Source: biomedcentral.com
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques: Severe acute respiratory syndrome coronavirus 2
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 20191,2 and is responsible for the COVID-19 pandemic3. Vaccines are an essential countermeasure urgently needed to control the pandemic4. Here, we...
Source: nature.com
Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
"Our collective dataset shows that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19."
Source: doi.org
Immunity to COVID-19 is probably higher than tests have shown: New research from Karolinska Institutet and Karolinska University
Immunity to COVID-19 is probably higher than tests have shown: New research from Karolinska Institutet and Karolinska University Hospital shows that many people with mild or asymptomatic COVID-19 demonstrate so-called T-cell-mediated immunity to the new coronavirus, even if they have not tested positively...
Source: news.ki.se
How the adults in the room handled the economic impact of COVID-19 in March - not the politicians and not their advisers.
"The adults in the room: On Sunday 15 March, the morning before he became the 121st governor of the Bank of England, Andrew Bailey absorbed the news from around the world. In the past 12 hours, the White House had banned all visitors from the UK, Spain had introduced a national lockdown, France had closed...
Source: newstatesman.com
SARS-CoV-2-specific T cell immunity is seen in cases of COVID-19
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls: Memory T cells induced by previous pathogens can shape the susceptibility to, and clinical severity of, subsequent infections1. Little is known about the presence of pre-existing memory T cells in humans with...
Source: nature.com
Climate campaigners win Heathrow expansion case: Campaigners say plans for a third runway should be cancelled, but the airport
Climate campaigners win Heathrow expansion case: Campaigners say plans for a third runway should be cancelled, but the airport says it will appeal.
Source: bbc.com
Energy conference cancelled after Royal College of General Practitioners concern.
Energy conference cancelled after College concern. Professor Martin Marshall, Chair of the Royal College of GPs, said: “We deeply regret that a booking was accepted to host an event at our headquarters that conflicts with the College’s longstanding commitment to combat the impact of climate change...
Source: rcgp.org.uk
The 100 Worst Ed-Tech Debacles of the Decade
The 100 Worst Ed-Tech Debacles of the Decade: "For the past ten years, I have written a lengthy year-end series, documenting some of the dominant narratives and trends in education technology. I think it is worthwhile, as the decade draws to a close, to review those stories and to see how much (or how...
Source: hackeducation.com
A kauri tree stump is kept alive by its neighbours through hydraulic coupling. Forests should be viewed as living organisms.
A kauri tree stump is kept alive by its neighbours through hydraulic coupling. Forests should be viewed as living organisms. "Trees are commonly regarded as distinct entities, but the roots of many species fuse to form natural root grafts allowing the exchange of water, carbon, mineral nutrients, and...
Source: cell.com
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’ style payment model to incentivise pharmaceutical companies to develop new drugs for resistant infections.
"The new trial will be led by the National Institute for...
Source: www.gov.uk
Humanitarian health computing using artificial intelligence and social media: A narrative literature review. "The feasibility
Humanitarian health computing using artificial intelligence and social media: A narrative literature review. "The feasibility of using AI to extract valuable information during a
humanitarian health crisis is proven in many cases. There is a lack of
research on how to integrate the use of AI into...
Source: nih.gov
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