Discovery of a structural class of antibiotics with explainable deep learning.
One of the challenges with deep learning (neural networks) is that although they find patterns the reasoning disappears into an endless detail of numbers. In this paper the researchers built an 'explainable' AI to discover antibiotics instead of such a 'black box'. "The discovery of novel structural...
Source: nature.com
6 expert essays on the future of biotech
How will biotechnology transform our approach to human health? Scientists from the World Economic Forum's Global Future Council share key insights. World Economic Forum future of biotech DNA technology - genetic screening for disease, recombinant protein production, CAR T cells, gene therapy, organoid...
Source: weforum.org
Fatalism - the stalemate of us vs. COVID-19
Stephen Casper - medical historian at Clarkson University - offers a worrying prediction for COVID for the end of 2022. The analogy for COVID-19 won't be influenza but 'tuberculosis before the discovery of antibiotics'. A new hospital specialty might even exist - looking after COVID patients - and they...
Source: twitter.com
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’ style payment model to incentivise pharmaceutical companies to develop new drugs for resistant infections.
"The new trial will be led by the National Institute for...
Source: www.gov.uk
Q&A: 'A chicken worth eating tastes like a chicken that had a life worth living': Maryn McKenna, author of Big Chicken,
Q&A: 'A chicken worth eating tastes like a chicken that had a life worth living': Maryn McKenna, author of Big Chicken, tells Lucy Rock how antibiotics created modern agriculture, changed the way we eat and gave rise to deadly superbugs
Source: theguardian.com
Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections
Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections | Cochrane
Source: cochrane.org
NICE right to advise against antibiotics for most ear infections
NICE right to advise against antibiotics for most ear infections
Source: rcgp.org.uk
Advice to "Complete the Course" of Most Antibiotics Seen as Unfounded: By Joe Elia Edited by Susan Sadoughi, MD The
Advice to "Complete the Course" of Most Antibiotics Seen as Unfounded: By Joe Elia
Edited by Susan Sadoughi, MD
The "deeply embedded" view that failing to complete a course of antibiotics will lead to drug resistance has no evidentiary basis, according to an analysis in The BMJ . … NEJM Journal...
Source: jwatch.org
WHO: 12 Bacteria Families Urgently Require New Antibiotics: By Kelly Young Edited by David G. Fairchild, MD, MPH The
WHO: 12 Bacteria Families Urgently Require New Antibiotics: By Kelly Young
Edited by David G. Fairchild, MD, MPH
The World Health Organization has listed 12 families of bacteria that "pose the greatest threat to human health" because of resistance to … NEJM Journal Watch.
Source: jwatch.org
Best way to stop overprescribing antibiotics? Public shaming, of course: Doctors may be as irrational as the rest of us
Best way to stop overprescribing antibiotics? Public shaming, of course: Doctors may be as irrational as the rest of us mere mortals, researchers say.
Source: arstechnica.com
Fewer antibiotics, better outcomes for complicated appendectomy patients?: With acute appendicitis ranking among the nation's
Fewer antibiotics, better outcomes for complicated appendectomy patients?: With acute appendicitis ranking among the nation's most common acute surgical emergencies, researchers studied the relatively routine use of post-operative antibiotics in complicated cases and found that they didn't reduce infections...
Source: medicalxpress.com
Nanodiamonds might prevent tooth loss after root canals: Nanodiamonds may help patients that have had the dreaded root canal.
Nanodiamonds might prevent tooth loss after root canals: Nanodiamonds may help patients that have had the dreaded root canal. UCLA dental researchers have developed a nanodiamond-reinforced version of gutta percha, the compound that is used to fill void spaces in dental root canals to prevent infection...
Source: eurekalert.org
Blood-cleansing biospleen device developed for sepsis therapy: Things can go downhill fast when a patient has sepsis, a
Blood-cleansing biospleen device developed for sepsis therapy: Things can go downhill fast when a patient has sepsis, a life-threatening condition in which bacteria or fungi multiply in a patient's bloodâoften too fast for antibiotics to help. A new device inspired by the human spleen and developed...
Source: medicalxpress.com
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