Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16%...
Source: nature.com
House passes $35-a-month insulin cap as Dems seek wider bill
WASHINGTON (AP) — The House on Thursday passed a bill capping the monthly cost of insulin at $35 for insured patients, part of an election-year push by Democrats for price curbs on prescription drugs at a time of rising inflation.
Source: apnews.com
The Bluestocking: The Ant Mill
The Ant Mill theory of Discourse. "An orphan take is an opinion expressed in backlash to a marginal, nebulous or anticipated opposing view. If you see angry tweets or opeds about the horror of a viewpoint you’ve never seen expressed in the wild, that’s an orphan take."
Source: substack.com
Biopharma futures
I've been looking at a few industry reports on the future of biopharma as part of a course I'm on with INSEAD Business School on Business Strategy and Financial Performance. I thought I'd share some of my ramblings on Biopharma Futures. Expectations are high Pharmaceutical
companies are operating...
Source: deanjenkins.me
What does the future of work look like for pharma?
The COVID-19 pandemic has accelerated changes to our working world. What does this mean for pharma, and what must the industry do to keep pace? PwC - future of work for pharma costs - pressures on efficienct, increasing R&D costs sustainability and societal impact - pressure on companies to address...
Source: pwc.co.uk
The 10 Trends Shaping the Future of Pharma - The Medical Futurist
The medical community gradually acknowledges digital health but doesn't embrace it entirely. Familiarize yourself with the future of pharma! Medical Futurist 10 trends shaping the future of pharma Patients on advisory boards - to better know the exact needs Digital health strategy 'around the pill'...
Source: medicalfuturist.com
Biopharma 2020: A landmark year and a reset for the future
Biopharma in 2020 has shown what it can achieve when it works at its best. How can the industry build on this renewed sense of purpose in the years ahead? McKinsey biopharma 2020 3 Overarching trends Operating under a spotlight - expectation of innovationNavigating protracted economic uncertainty -...
Source: mckinsey.com
The future of biopharma
Shifts in how diseases are diagnosed and prevented, custom treatments, curative therapies, digital therapeutics, and precision intervention could upend current business models in biopharma. Deloitte's Five forces to 2040 Prevention and early detection Customized treatments - interventions for very...
Source: deloitte.com
The women who fought against nuclear missiles
The Greenham Common anti-nuclear protest was the UK's biggest women-led movement since the Suffragettes.
Source: bbc.co.uk
Climate activists buy environment secretary's Cornwall constituency office
"Insulate Britain supporters donate rent from George Eustice MP's HQ towards protesters' court costs." Landlord activism.
Source: theguardian.com
Fusion energy record demonstrates powerplant future
"Landmark results from EUROfusion scientists and engineers at world-leading UK Atomic Energy Authority’s Joint European Torus (JET) facility in Oxford. "Record-breaking 59 megajoules of sustained fusion energy demonstrates powerplant potential and strengthens case for ITER." "The record and scientific...
Source: ukaea.uk
Morgan Stanley: Global oil supply likely to peak earlier than demand
"Global oil supply is likely to peak even earlier than demand, Morgan Stanley said in a research note, based on its analysis on current trends." What does this mean? Investment in new oil and gas is falling because of policies to phase it out. This means the supply of fossil fuels will peak (or has peaked)...
Combat drones: We are in a new era of warfare - here's why
No longer the preserve of superpowers, drones are now in the hands of insurgents and smaller countries.
Source: bbc.com
Thich Nhat Hanh, poetic peace activist and master of mindfulness, dies at 95
Thich Nhat Hanh, the Zen Buddhist monk, poet and peace activist who in the 1960s came to prominence as an opponent of the Vietnam War, died on Saturday aged 95 surrounded by his followers in the temple where his spiritual journey began. "Hope is important, because it can make the present moment less...
Source: reuters.com
Fatalism - the stalemate of us vs. COVID-19
Stephen Casper - medical historian at Clarkson University - offers a worrying prediction for COVID for the end of 2022. The analogy for COVID-19 won't be influenza but 'tuberculosis before the discovery of antibiotics'. A new hospital specialty might even exist - looking after COVID patients - and they...
Source: twitter.com
Factors affecting the uptake of new medicines: a systematic literature review - BMC Health Services Research Lublóy, Ágnes.
"This systematic literature review has provided insights into the factors that affect new drug uptake—primarily, doctors’ scientific orientation, prescribing habits, exposure to pharmaceutical marketing, and interpersonal communication." "Background The successful diffusion of new drugs is crucial...
Source: biomedcentral.com
The unhealthy industry playbook
What Public Health Practitioners Need to Know About Unhealthy IndustryTactics. Attack legitimate science. e.g. Accuse science of deception, calling it “junk science” or “bad science,” claiming science is manipulated to fulfill a political agenda. Attack and intimidate the scientists. e.g. Create...
Source: aphapublications.org
Early warnings and emerging accountability: Total's responses to global warming, 1971-2021 Global Environmental Change.
Building upon recent work on other major fossil fuel companies, we report new archival research and primary source interviews describing how Total responded to evolving climate science and policy in the last 50 years. We show that Total personnel received warnings of the potential for catastrophic global...
Source: sciencedirect.com
Overturning 'conventional wisdom' with 'natural experiments'
Via Reuters ... "Economists David Card, Joshua Angrist and Guido Imbens won the 2021 Nobel economics prize on Monday for pioneering "natural experiments" to show real-world economic impacts in areas from minimum wage increases in the U.S. fast-food sector to migration from Castro-era Cuba." "One experiment...
Source: reuters.com
Psychology of panic buying
I've been fascinated by the psychology of panic buying and it is clearly an area for future research. It has an enormous impact on delivery infrastructure and I wonder if anyone has been tracking the data of the causes and the impact in the current fuel 'crisis'. A systematic review from last year identified...
Source: nih.gov
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