Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound, injected in to CSF and designed to reduce the production of all forms of the huntingtin (HTT) protein, which in its mutated variant (mHTT) is responsible for Huntington's Disease....
Source: reuters.com
Pimp My Zimmer project 'reduces falls': Care home residents in Wales have been decorating their Zimmer frames to make them more identifiable.
Source: bbc.co.uk
Innovating Pedagogy 2017 - The Ed Techie "The Open University’s annual Innovating Pedagogy report is out." I enjoy these summaries of emerging technologies in education from the Open University. Look out for some of these on a learning programme near you sometime soon. What is really interesting...
Source: edtechie.net
Meta‐analysis of the procedural risks of carotid endarterectomy and carotid artery stenting over time: Stroke/death rates within 30 days of carotid endarterectomy (CEA) and carotid artery stenting (CAS) in RCTs inform current clinical guidelines. However, the risks may have changed in recent years...
Source: wiley.com
DeepMind AI needs mere 4 hours of self-training to become a chess overlord: AlphaGo Zero needed three days to train up in Go; AlphaZero needed just eight hours.
Source: arstechnica.com
The future is here: Genetically engineered stem cells save a patient: The genetic disease epidermolysis bullosa left a patient without much skin.
Source: arstechnica.com
Association Between Treatment by Locum Tenens Internal Medicine Physicians and 30-Day Mortality Among Hospitalized Medicare Beneficiaries: This cohort study evaluates the differences in quality and costs of care related to locum tenens vs non–locum tenens physicians treating hospitalized Medicare beneficiaries....
Source: jamanetwork.com
What to Do When a Patient Has a 'Do Not Resuscitate' Tattoo: “We’ve always joked about this, but holy crap, this man actually did it.” This is a good account in The Atlantic and highlights the ethical debate about consent. Many doctor and medico-legal comments have been circulating on social media...
Source: theatlantic.com
Do Good on Autopilot (i.e. without even thinking about it) with These 4 Apps. The apps (mostly plugins to browsers) help with raising money for charitable causes without you having to do anything other than install the app.
Source: thelifeyoucansave.org
After 37 years, Voyager 1 has fired up its trajectory thrusters: This week, the scientists and engineers on the Voyager team did something very special. What does this mean for Voyager and what effect will this thrust have on its trajectory? Great that the rockets work - fantastic engineering - and...
Source: arstechnica.com
Blind Obedience and an Unnecessary Workup for Hypoglycemia: A Teachable Moment: This Teachable Moment examines the danger in overvaluing laboratory test results that contradict clinical findings. Elizabeth Y. Wang. Lauren Patrick. Denise M. Connor. JAMA Internal Medicine.
Source: jamanetwork.com
How to brew beer like a Norwegian farmer: Kveik: a word we’re likely to be seeing a lot more of in the beer world. But what is kveik? Here are a couple of things it’s not: Kveik is NOT a beer style. It’s the name given in…
Source: zythophile.co.uk
Insulin-sensitising drugs for women with a diagnosis of polycystic ovary syndrome and subfertility | Cochrane
Source: cochrane.org
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis: Objective To compare the efficacy, safety, and cost effectiveness of direct acting oral anticoagulants (DOACs) for patients with atrial fibrillation.
Design...
Source: bmj.com
Thyroid drug to stay on the NHS: The decision on liothyronine was part of a wider prescribing review by NHS England.
Source: bbc.co.uk
Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study combined themes in cardiovascular modelling, clinical cardiology and e-learning to create an on-line environment that would assist undergraduate medical students in understanding...
Source: biomedcentral.com
Flare - an app that connects people and emergency response vehicles in Kenya. "How a speedy emergency services app is saving lives: Not every country has a single number to call in an emergency. One start-up is trying to change that."
Source: bbc.co.uk
A stable plasma ring has been created in open air for the first time ever: Researchers say it's "essentially capturing lightning in a bottle, but without the bottle."
Source: futurism.com
A cross-sectional examination of psychological distress, positive mental health and their predictors in medical students in their clinical clerkships: Medical students can experience the transition from theory to clinical clerkships as stressful. Scientific literature on the mental health of clinical...
Source: biomedcentral.com
Linking primary schools and care homes with letter writing pen pals. A great initiative that helps language skills and creative writing for children whilst also enabling otherwise isolated elders share memories and make new friends. I heard this story first on the radio with great examples of the types...
Source: bbc.co.uk