Milasen - a drug developed for a single patient.
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
Eisai launches a digital health solution on Amazon Alexa for children with a rare form of epilepsy - Lennox-Gastaut Syndrome.
It marks the first time Pharmaceutical company Eisai has moved beyond medications and into digital health. The company’s Amazon Alexa skill – Ella the Jellyfish – has been developed for children with Lennox-Gastaut Syndrome (LGS) and was created with input from patients, their families and caregivers.
Source: epmmagazine.com
The Collective Journey storytelling model
The Collective Journey is a way of explaining and retelling why something from the complex world has happened. Whilst it is a tool for storytellers to make compelling entertainment it also highlights the weakness of the single perspective in trying to understand the real world. “For centuries, every...
Source: collectivejourney.com
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study.
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study. Designing learning for person-centred care is challenging and needs to involve an approach that works with HCPs and interdisciplinary teams. “With increasing numbers of people in the UK...
Source: biomedcentral.com
Teaching a difficult topic in medical genetics using a problem-based concept resembling a computer game.
Teaching a difficult topic using a problem-based concept resembling a computer game: development and evaluation of an e-learning application for medical molecular genetics: E-learning through serious gaming. Teaching concepts such as genetic testing and the digital literacy required to analyse data can...
Source: biomedcentral.com
Physicians reported less burnout and emotional exhaustion after receiving short-term professional coaching.
Physicians reported less burnout and emotional exhaustion after receiving short-term professional coaching, according to a pilot trial published in JAMA Internal Medicine. Counseling Reduces Physician Burnout Anita Slomski. JAMA. 2019;322(16):1544 This editorial in JAMA comments on the recent paper:...
Source: jamanetwork.com
Training medical students to manage difficult circumstances- a curriculum for resilience and resourcefulness?: In response
Training medical students to manage difficult circumstances- a curriculum for resilience and resourcefulness?: In response to the growing prevalence of physical and emotional burnout amongst medical students and practicing physicians, we sought to find a new methodology to scope a five-year undergraduate...
Source: biomedcentral.com
Measles is killing more people in the DRC than Ebola—and faster: "Frankly, I am embarrassed to talk only about Ebola,"
Measles is killing more people in the DRC than Ebola—and faster: "Frankly, I am embarrassed to talk only about Ebola," WHO director-general says. Since January 2019, officials have recorded over 100,000 measles cases in the DRC, mostly in children, and nearly 2,000 have died. The figures surpass those...
Source: arstechnica.com
A New Model for Integrating Behavioral Science and Design. Part of the ‘Nudge turns 10’ issue. A model for being creative
A New Model for Integrating Behavioral Science and Design. Part of the ‘Nudge turns 10’ issue. A model for being creative with design informed by behavioural science.
“Thaler and Sunstein knew that nudges were a piece of the behavioral change puzzle but not the only piece. So what’s missing?”...
Source: behavioralscientist.org
Phrase of the day: "Future-directed Postfactual Speculation". A planning technique ('backcasting' - analogous to 'forecasting')
Phrase of the day: "Future-directed Postfactual Speculation". A planning technique ('backcasting' - analogous to 'forecasting') for deciding what steps would need to be taken to reach a particular future state. Used by futurists to help identify important factors that may lie ahead. "Backcasting is increasingly...
Source: wikipedia.org
Factors Affecting the Development and Sustainability of Communities of Practice Among Primary Care Physicians in Hong Kong.
Factors Affecting the Development and Sustainability of Communities of Practice Among Primary Care Physicians in Hong Kong. "Autonomy of group learning
activities, recruiting specialists and allied health professionals,
training facilitators, and undertaking discussion in multimedia may
achieve...
Source: nih.gov
Instead of building (only) strong relationships we should aim for many acquaintances. There is resilience for organisations
Instead of building (only) strong relationships we should aim for many acquaintances. There is resilience for organisations and communities in these weak ties. Granovetter’s theory of the strength of weak ties.
Source: analytictech.com
Utility of social media and crowd-intelligence data for pharmacovigilance: a scoping review. - PubMed - NCBI "Although
Utility of social media and crowd-intelligence data for pharmacovigilance: a scoping review. - PubMed - NCBI "Although social media data has the potential to supplement data from
regulatory agency databases; is able to capture less frequently reported
AEs; and can identify AEs earlier than official...
Source: nih.gov
Wales' Brexit vote had deeper roots than many are willing to admit: Martin Johnes, Professor of History at Swansea University
Wales' Brexit vote had deeper roots than many are willing to admit: Martin Johnes, Professor of History at Swansea University The Brexit vote was a profound shock to those who like to believe that Wales has a distinctive and progressive culture. It is little wonder that people looked for someone to...
Source: nation.cymru
Playbook for Launching a Local, Nonprofit News Outlet - Shorenstein Center: This playbook was written as part of a policy
Playbook for Launching a Local, Nonprofit News Outlet - Shorenstein Center: This playbook was written as part of a policy analysis exercise (PAE), an academic project where Harvard Kennedy School (HKS) students develop solutions for a public or nonprofit sector policy or management issue presented by...
Source: shorensteincenter.org
Wristband with Sensors to Improve Lives of Dementia Patients. "At the Fraunhofer Institute for Reliability and Microintegration
Wristband with Sensors to Improve Lives of Dementia Patients. "At the Fraunhofer Institute for Reliability and Microintegration in Berlin, Germany researchers are working on a sensor and software package that would help people developing dementia to slow down the disease progression [by this I presume...
Source: medgadget.com
Frozen Pluto has wind-blown dunes made of methane sand. The same complex forces that make the patterns in our world that
Frozen Pluto has wind-blown dunes made of methane sand. The same complex forces that make the patterns in our world that we so admire also work in alien worlds but, as in Pluto, on substances that would be truly exotic here on earth.
Source: arstechnica.com
Simulation based education and expansive learning in health professional education: A discussion: The aim of this paper
Simulation based education and expansive learning in health professional education: A discussion: The aim of this paper is to discuss the application of Simulation Based Education (SBE) in nursing and wider health professional education. Simulated Learning (SL) is discussed in relation to its history,...
Source: journals.sfu.ca
Winners of the 2018 PLOS Computational Biology Research Prize | PLOS Biologue: It's time to celebrate the best of PLOS
Winners of the 2018 PLOS Computational Biology Research Prize | PLOS Biologue: It's time to celebrate the best of PLOS Computational Biology! In 2017 PLOS Computational Biology launched the "PLOS Computational Biology Research Prize" program with the aim to recognize some of the journal's most outstanding...
Source: plos.org
Healthcare students' perceptions about their role, confidence and competence to deliver brief public health interventions
Healthcare students' perceptions about their role, confidence and competence to deliver brief public health interventions and advice: Public health improvement has long been an important focus for the United Kingdom Department of Health. The Allied Health Professions (AHP) Federation has 84,000 members,...
Source: biomedcentral.com
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