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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million

We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16%...
Source: nature.com

How the War in Ukraine Could Get Much Worse

The West and Russia may be entering into the terminal stages of an insecurity spiral, which could produce a larger European war even if it doesn’t go nuclear.
Source: foreignaffairs.com

Biopharma futures

blog post image I've been looking at a few industry reports on the future of biopharma as part of a course I'm on with INSEAD Business School on Business Strategy and Financial Performance. I thought I'd share some of my ramblings on Biopharma Futures. Expectations are high Pharmaceutical companies are operating...
Source: deanjenkins.me

Biopharma 2020: A landmark year and a reset for the future

Biopharma in 2020 has shown what it can achieve when it works at its best. How can the industry build on this renewed sense of purpose in the years ahead? McKinsey biopharma 2020 3 Overarching trends Operating under a spotlight - expectation of innovationNavigating protracted economic uncertainty -...
Source: mckinsey.com

Internet user classification

Grampound it seems is classified as 'e-Rational Utilitarian' ... but who is shouting out for more local facilities and better internet infrastructure? Checks notes ... methodological individualist and political liberals with social stratification (i.e. class, status distinctions) playing a relatively...
Source: cdrc.ac.uk

Britishvolt: Electric car battery plant gets government funding

Britishvolt says the money (£100m) unlocks huge private investment for a protect that will create thousands of jobs. See also Britishvolt.com The figure seems to be half of the proposed Government investment which was anticipated to be £200m - £250m in December.
Source: bbc.com

Fatalism - the stalemate of us vs. COVID-19

Stephen Casper - medical historian at Clarkson University - offers a worrying prediction for COVID for the end of 2022. The analogy for COVID-19 won't be influenza but 'tuberculosis before the discovery of antibiotics'. A new hospital specialty might even exist - looking after COVID patients - and they...
Source: twitter.com

Factors affecting the uptake of new medicines: a systematic literature review - BMC Health Services Research Lublóy, Ágnes.

"This systematic literature review has provided insights into the factors that affect new drug uptake—primarily, doctors’ scientific orientation, prescribing habits, exposure to pharmaceutical marketing, and interpersonal communication." "Background The successful diffusion of new drugs is crucial...
Source: biomedcentral.com

Meet the rogue birding group blocking wind energy at every turn

The American Bird Conservancy has repeatedly obstructed wind energy projects and become a go-to source for renewable energy opponents.
Source: grist.org

Rocking down to Electric Avenue? Good luck charging your car

European and U.S. cities planning to phase out combustion engines over the next 15 years first need to plug a charging gap for millions of residents who park their cars on the street.
Source: reuters.com

China has won AI battle with U.S., Pentagon's ex-software chief says

China has won the artificial intelligence battle with the United States and is heading towards global dominance because of its technological advances, the Pentagon's former software chief told the Financial Times.
Source: reuters.com

The AI Hierarchy of Needs | Hacker Noon

Sometimes you come across something that someone has written which makes what was a whole complicated mess in your head very simple indeed. Monica Rogati has done that with AI using an analogy of Maslow's (in)famous hierarchy of needs. For AI it translates to something like collecting, storing, preparing,...
Source: hackernoon.com

Psychology of panic buying

I've been fascinated by the psychology of panic buying and it is clearly an area for future research. It has an enormous impact on delivery infrastructure and I wonder if anyone has been tracking the data of the causes and the impact in the current fuel 'crisis'. A systematic review from last year identified...
Source: nih.gov

Rediscovering Cryptpad

Cryptpad is for working collaboratively on documents such as Rich Text, Spread Sheets, Presentations, Whiteboards, and Project Boards. The server has no access to any of your data and the encryption is based on zero knowledge. You don't even need to give an email address to register - you pick a username...
Source: cryptpad.fr

New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution

"Air pollution is one of the biggest environmental threats to human health, alongside climate change. New guidelines provide clear evidence of the damage air pollution inflicts on human health, at even lower concentrations than previously understood." "Global assessments of ambient air pollution alone...
Source: who.int

The Impact of Mask Distribution and Promotion on Mask Uptake and COVID-19 in Bangladesh

A growing body of scientific evidence suggests that face masks can protect against COVID-19. There is, however, limited rigorous evidence on the extent to which mask-wearing is effective in reducing COVID-19 in a real-life situation with imperfect and inconsistent mask use. In Bangladesh, researchers...
Source: poverty-action.org

Extinction Rebellion protesters block London's Tower Bridge

Demonstrators from the Extinction Rebellion group, which is demanding urgent action by governments and business to limit climate change and biodiversity loss, staged a sit-down protest that stopped traffic from using Tower Bridge in London on Monday.
Source: reuters.com

Development and validation of teacher and student questionnaires measuring inhibitors of curriculum viability - BMC Medical

Background Curriculum viability is determined by the degree to which quality standards have or have not been met, and by the inhibitors that affect attainment of those standards. The literature reports many ways to evaluate whether a curriculum reaches its quality standards, but less attention is paid...
Source: biomedcentral.com

Council policies 'inconsistent' with climate goals

A third of English councils support policies that could increase emissions, BBC research suggests.
Source: bbc.com

OpenAI's Codex Translates Everyday Language Into Computer Code

The company believes its Codex machine learning algorithm is the next step in programming—a sidekick for coders to speed up the work and ease the drudgery.
Source: singularityhub.com