First drug to reverse Huntington's disease begins human trials : The new drug, called IONIS-HTTRx, silences the gene known
First drug to reverse Huntington's disease begins human trials : The new drug, called IONIS-HTTRx, silences the gene known to be responsible for the production of a protein which causes Huntington’s
Source: telegraph.co.uk
Just finished reading "Dancing at the edge" an exploration of competencies for the 21st century. An excellent and academic
Just finished reading "Dancing at the edge" an exploration of competencies for the 21st century. An excellent and academic review of the topic giving hope that "future persons" will indeed be more resilient. Instead of simply listing competencies they describe examples from the extensive range of interviews...
Source: internationalfuturesforum.com
Psychology’s reproducibility problem is exaggerated – say psychologists: Reanalysis of last year's enormous replication
Psychology’s reproducibility problem is exaggerated – say psychologists: Reanalysis of last year's enormous replication study argues that there is no need to be so pessimistic. Nature News.
Source: nature.com
Colombia doctor reports first case of Zika-linked microcephaly: The first case of birth defect microcephaly linked to the
Colombia doctor reports first case of Zika-linked microcephaly: The first case of birth defect microcephaly linked to the mosquito-borne Zika virus has appeared in Colombia, a doctor said on Friday, although the national health institute said it had no information on the case and could not confirm it....
Source: reuters.com
Next Generation Learning Analytics: Or, How Learning Analytics is Passé: "'Learning Analytics,' as so many know it, is
Next Generation Learning Analytics: Or, How Learning Analytics is Passé: "'Learning Analytics,' as so many know it, is already passé. There is almost always a disconnect between research innovation and the popular imagination. By the time a new concept or approach achieves widespread acceptance, its...
Source: timothyharfield.com
"In its ongoing effort to make MOOCs more and more like traditional education, Coursera has launched 'mentor-guided courses'
"In its ongoing effort to make MOOCs more and more like traditional
education, Coursera has launched 'mentor-guided courses' for the cost of
$US 248." I like Stephen Downes and the way he pokes fun at the big MOOC companies. Their aim though is simply to try and monetize their courses. The mentor...
Source: downes.ca
Donald Clark Plan B: The LMS is dead, long live the LMS! (10 pros & 10 cons)
Donald Clark Plan B: The LMS is dead, long live the LMS! (10 pros & 10 cons)
Source: blogspot.co.uk
The Religious Roots of Shaming-as-Rehab Programs: The harsh tactics of some unregulated addiction-therapy groups have parallels
The Religious Roots of Shaming-as-Rehab Programs: The harsh tactics of some unregulated addiction-therapy groups have parallels in monastic tradition.
Source: theatlantic.com
Evolution seems to have occurred a million times faster than natural selection alone could explain. Could nature be using
Evolution seems to have occurred a million times faster than natural selection alone could explain. Could nature be using some hidden process? Just read Probably Approximately Correct by Leslie Valiant (a computational theorist). It explores a special class of algorithms which he calls 'ecorthims' that...
Source: amazon.co.uk
Statin-Associated Autoimmune Myopathy - Now@NEJM: Statins significantly reduce the incidence of cardiovascular disease,
Statin-Associated Autoimmune Myopathy - Now@NEJM: Statins significantly reduce the incidence of cardiovascular disease, are generally safe, and have an acceptable side-effect profile. It is now recognized, however, that in very rare cases, an autoimmune myopathy develops in patients treated with statins;...
Source: nejm.org
"to truly improve health equity, we need to swim even further upstream and engage in advocacy for an entire population.
"to truly improve health equity, we need to swim even further upstream and engage in advocacy for an entire population. The WHO Commission on the Social Determinants of Health was explicit that to achieve health equity, we need to tackle the inequitable distribution of power, money and resources". Swimming...
Source: bmj.com
The problem with Plan-Do-Study-Act cycles
"This article presents our reflections on the full potential of using PDSA in healthcare, but in doing so we explore the inherent complexity and multiple challenges of executing PDSA well. Ultimately, we argue that the problem with PDSA is the oversimplification of the method as it has been translated...
Source: bmj.com
10 ways MOOCs have forced Universities into a rethink. "MOOCs have made us think. As one of the most fascinating developments
10 ways MOOCs have forced Universities into a rethink. "MOOCs have made us think. As one of the most fascinating developments in
higher education in my lifetime, they are,in many ways, a pioneer of a
more ‘open’ spirit
in learning. I’d contend that MOOCs, for all their promises and faults,...
Source: blogspot.co.uk
Unified theory of ‘learning’ emerges – and it’s mind blowing. "You’ve probably never heard of James Mark Baldwin,
Unified theory of ‘learning’ emerges – and it’s mind blowing. "You’ve
probably never heard of James Mark Baldwin, yet he turned out be one of the greats in learning theory. A 19th century psychologist, he
introduced what is called the ‘Baldwin Effect’ into evolutionary theory."
Source: blogspot.co.uk
Establishing hydrogen infrastructure is not an insurmountable problem. Whatever you may have heard. Riversimple’s Finance
Establishing hydrogen infrastructure is not an insurmountable problem. Whatever you may have heard. Riversimple’s Finance Director, Jeff Loo, likens the current Hydrogen infrastructure to the (lack of) early cell phone masts. This is an exciting Welsh start-up, in Llandrindod Wells, is aiming to build...
Source: riversimple.com
RtoP. I've been privileged to work on this programme for the past 18 months with Trish groves at BMJ and now very happy
RtoP. I've been privileged to work on this programme for the past 18 months with Trish groves at BMJ and now very happy to see it launched. It is a collaboration between UCSF and BMJ bringing together the two great themes of conducting great research and getting it published. Visit rtop.bmj.com to try...
Source: bmj.com
Citable Items: The Contested Impact Factor Denominator: Thomson Reuters' approach of indexing by journal section and revising
Citable Items: The Contested Impact Factor Denominator: Thomson Reuters' approach of indexing by journal section and revising by demand leads to great inconsistencies across journals and inflates the Impact Factors of elite journals. The solution: remov...
Source: sspnet.org
Just finished reading Edgar Schein's Humble Inquiry: the gentle are of asking instead of telling. Edgar Schein is the Professor
Just finished reading Edgar Schein's Humble Inquiry: the gentle are of asking instead of telling. Edgar Schein is the Professor of Management Emeritus at MIT Sloan School of Management. This simply written and short book communicates his life's work on organisational psychology. Very well written. ...
Source: amazon.co.uk
Just finished reading Enabling Collaboration - a book on "achieving success through strategic alliances and partnerships"
Just finished reading Enabling Collaboration - a book on "achieving success through strategic alliances and partnerships" by Martin Echavarria (@coherence360). Getting things done invariably involves working with others and when those others are themselves complex organisations it requires some thought....
Source: enablingcollaboration.com
What are the Costs and Benefits of Providing Comprehensive Seven‐day Services for Emergency Hospital Admissions? Meacock,
What are the Costs and Benefits of Providing Comprehensive Seven‐day Services for Emergency Hospital Admissions? Meacock, Rachel. Doran, Tim. Sutton, Matt. Health Economics. "There is as yet no clear evidence that 7-day services will reduce
weekend deaths or can be achieved without increasing weekday...
Source: wiley.com
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