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Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound,

Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound, injected in to CSF and designed to reduce the production of all forms of the huntingtin (HTT) protein, which in its mutated variant (mHTT) is responsible for Huntington's Disease....
Source: reuters.com

DeepMind AI needs mere 4 hours of self-training to become a chess overlord: AlphaGo Zero needed three days to train up in

DeepMind AI needs mere 4 hours of self-training to become a chess overlord: AlphaGo Zero needed three days to train up in Go; AlphaZero needed just eight hours.
Source: arstechnica.com

Association Between Treatment by Locum Tenens Internal Medicine Physicians and 30-Day Mortality Among Hospitalized Medicare

Association Between Treatment by Locum Tenens Internal Medicine Physicians and 30-Day Mortality Among Hospitalized Medicare Beneficiaries: This cohort study evaluates the differences in quality and costs of care related to locum tenens vs non–locum tenens physicians treating hospitalized Medicare beneficiaries....
Source: jamanetwork.com

What to Do When a Patient Has a 'Do Not Resuscitate' Tattoo: “We’ve always joked about this, but holy crap, this man

What to Do When a Patient Has a 'Do Not Resuscitate' Tattoo: “We’ve always joked about this, but holy crap, this man actually did it.” This is a good account in The Atlantic and highlights the ethical debate about consent. Many doctor and medico-legal comments have been circulating on social media...
Source: theatlantic.com

Do Good on Autopilot (i.e. without even thinking about it) with These 4 Apps. The apps (mostly plugins to browsers) help

Do Good on Autopilot (i.e. without even thinking about it) with These 4 Apps. The apps (mostly plugins to browsers) help with raising money for charitable causes without you having to do anything other than install the app.
Source: thelifeyoucansave.org

After 37 years, Voyager 1 has fired up its trajectory thrusters: This week, the scientists and engineers on the Voyager

After 37 years, Voyager 1 has fired up its trajectory thrusters: This week, the scientists and engineers on the Voyager team did something very special. What does this mean for Voyager and what effect will this thrust have on its trajectory? Great that the rockets work - fantastic engineering - and...
Source: arstechnica.com

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis: Objective To compare the efficacy, safety, and cost effectiveness of direct acting oral anticoagulants (DOACs) for patients with atrial fibrillation. Design...
Source: bmj.com

Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study

Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study combined themes in cardiovascular modelling, clinical cardiology and e-learning to create an on-line environment that would assist undergraduate medical students in understanding...
Source: biomedcentral.com

Flare - an app that connects people and emergency response vehicles in Kenya. "How a speedy emergency services app is saving

Flare - an app that connects people and emergency response vehicles in Kenya. "How a speedy emergency services app is saving lives: Not every country has a single number to call in an emergency. One start-up is trying to change that."
Source: bbc.co.uk

A cross-sectional examination of psychological distress, positive mental health and their predictors in medical students

A cross-sectional examination of psychological distress, positive mental health and their predictors in medical students in their clinical clerkships: Medical students can experience the transition from theory to clinical clerkships as stressful. Scientific literature on the mental health of clinical...
Source: biomedcentral.com

How one country persuaded teens to give up drink and drugs: Iceland used to have a big teenage drinking, smoking and drug

How one country persuaded teens to give up drink and drugs: Iceland used to have a big teenage drinking, smoking and drug problem. Now it doesn't.
Source: bbc.co.uk

Algorithm outperforms radiologists at diagnosing pneumonia | Stanford News: In just over a month of development, their algorithm

Algorithm outperforms radiologists at diagnosing pneumonia | Stanford News: In just over a month of development, their algorithm outperformed expert radiologists at diagnosing pneumonia.
Source: stanford.edu

Towards a Competence-Based Course Authoring Tool Supporting Learning Management Systems: To establish a more comparable,

Towards a Competence-Based Course Authoring Tool Supporting Learning Management Systems: To establish a more comparable, compatible, and coherent system of higher education in Europe, the so-called Bologna Process (BP) has been adopted. As a measure to improve comparability, the BP requires that every...
Source: online-journals.org

A model for the use of blended learning in large group teaching sessions: Although blended learning has the potential to

A model for the use of blended learning in large group teaching sessions: Although blended learning has the potential to enhance the student experience, both in terms of engagement and flexibility, it can be difficult to effectively restructure existing courses. To achieve these goals for an introductory...
Source: biomedcentral.com

Using social media to support small group learning: Medical curricula are increasingly using small group learning and less

Using social media to support small group learning: Medical curricula are increasingly using small group learning and less didactic lecture-based teaching. This creates new challenges and opportunities in how students are best supported with information technology. We explored how university-supported...
Source: biomedcentral.com

The DPCC-MS communication skills competency instrument. A simple 5 item instrument. "Validation of the 5-item doctor-patient

The DPCC-MS communication skills competency instrument. A simple 5 item instrument. "Validation of the 5-item doctor-patient communication competency instrument for medical students (DPCC-MS) using two years of assessment data: Medical students on clinical rotations have to be assessed on several competencies...
Source: biomedcentral.com

Could analysing personalised learning be better matched if physicians are first classified into competency groups? Using

Could analysing personalised learning be better matched if physicians are first classified into competency groups? Using latent class analysis to identify physician competency reveals four distinct subgroups in this cross-sectional study in China. The survey tool is large at over 100 items long but included...
Source: biomedcentral.com

What do Japanese residents learn from treating dying patients? The implications for training in end-of-life care: How medical

What do Japanese residents learn from treating dying patients? The implications for training in end-of-life care: How medical residents’ experiences with care for dying patients affect their emotional well-being, their learning outcomes, and the formation of their professional identities is not fully...
Source: biomedcentral.com

The Health and Social Care Act of 2012 - making GPs lead Clinical Commissioning Groups - did not reduce overall hospitalisations

The Health and Social Care Act of 2012 - making GPs lead Clinical Commissioning Groups - did not reduce overall hospitalisations study concludes. "[G]iving control of healthcare budgets to GP-led CCGs was not associated with a reduction in overall hospitalisations and was associated with an increase...
Source: plos.org

Denying patients NHS treatment based on lifestyle factors is not conducive to a good doctor-patient relationship. In response

Denying patients NHS treatment based on lifestyle factors is not conducive to a good doctor-patient relationship. In response to the Hertfordshire Valley CCG’s decision to restrict access to routine surgery until morbidly obese patients have lost weight, or smokers have given up, as discussed...
Source: rcgp.org.uk