Milasen - a drug developed for a single patient.
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
After the morning after: what next for UK trade policy? - Trade Knowledge Exchange: In the aftermath of the UK General Elections,
After the morning after: what next for UK trade policy? - Trade Knowledge Exchange: In the aftermath of the UK General Elections, in which the Conservatives won 364 out of 650 seats in House of Commons, the question that arises is what this means for the UK and the EU. “Getting Brexit done” was,...
Source: trade-knowledge.net
People in Japan are wearing exoskeletons to keep working as they age: To solve the problem of Japan’s ageing workforce,
People in Japan are wearing exoskeletons to keep working as they age: To solve the problem of Japan’s ageing workforce, tech companies have developed exoskeletons that help older workers continue to do heavy manual labour
Source: newscientist.com
Cardiac guidelines challenged following investigation.
Surgeons withdraw support for heart disease advice: European guidelines on a form of heart disease are under review, following a Newsnight investigation. “It is a matter of serious concern to us that some results in the Excel trial appear to have been concealed and that some patients may therefore...
Source: bbc.com
Animated video can more cost-effectively reach the widest – even geographically isolated – populations, it readily
Animated video can more cost-effectively reach the widest – even
geographically isolated – populations, it readily complements extension
services and international development community efforts to secure
knowledge transfer and recipient buy-in for innovations. Implications
and future research...
Source: tandfonline.com
20 optical illusions and how they work.
Our vision works very differently to how we assume it might work. It uses a lot of shortcuts to quickly decipher the world and those shortcuts are usually correct. Sometimes though, our vision is fooled and it these quirky areas of processing where optical illusions work. This great list id from Listverse.
Source: listverse.com
Archivists Are Trying to Make Sure a
Archivists Are Trying to Make Sure a ‘Pirate Bay of Science’ Never Goes Down: A new project aims to make LibGen, which hosts 33 terabytes of scientific papers and books, much more stable. "It’s hard to find free and open access to scientific material online. The latest studies and current research...
Source: vice.com
Would you pay $1 million to enroll in a phase 1 clinical trial of an
Would you pay $1 million to enroll in a phase 1 clinical trial of an “anti-aging” gene therapy? "Libella Gene Therapeutics, LLC made the news last week for announcing a “pay-to-play” trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it...
Source: sciencebasedmedicine.org
Yes you can learn surgery via YouTube
"Doctors are turning to YouTube to learn how to do surgical procedures, but there's no quality control: Tens of thousands of videos on YouTube show surgeries ranging from face-lifts to knee replacements. But the content isn't vetted or curated, and some doctors say it should be." The platform dominance...
Source: cnbc.com
Archaeologists found 143 more images among the Nazca Lines: The team used a machine-learning algorithm to search aerial
Archaeologists found 143 more images among the Nazca Lines: The team used a machine-learning algorithm to search aerial photos for geoglyphs.
Source: arstechnica.com
Australia Rolls Out AI-Powered Phone Detection Road Cameras - ExtremeTech: The Australian state of New South Wales is the
Australia Rolls Out AI-Powered Phone Detection Road Cameras - ExtremeTech: The Australian state of New South Wales is the first in the world to deploy phone detection cameras on its roads.
Source: extremetech.com
Drugmaker to Test Machine Learning to Prevent Drug Shortages: Germany-based Merck plans to use analytics and machine learning
Drugmaker to Test Machine Learning to Prevent Drug Shortages: Germany-based Merck plans to use analytics and machine learning to predict and prevent drug shortages, a move that could also save it money.
Source: wsj.com
Video for learning
Video for learning is great at some things, not so great at others. Great summary of recent evidence from Donald Clark. What can we learn from Netflix? (Use technology appropriately not just the buzzwords) Episodic vs. Semantic memory (Remembering the right things from video isn't as easy as you think)...
Source: blogspot.com
A Promising Solar Energy Breakthrough Just Achieved 1,000-Degree Heat From Sunlight: A new startup backed by Bill Gates
A Promising Solar Energy Breakthrough Just Achieved 1,000-Degree Heat From Sunlight: A new startup backed by Bill Gates says it has managed to harness solar energy to greater effect than ever before, generating enough heat from a field of mirrored panels to drive the production of cement, steel and glass...
Source: sciencealert.com
'If you think competition is hard, you should try collaboration.'
Leading for integrated care: This report explores the progress, challenges and opportunities the move towards greater integration presents, through interviews with 16 people leading or chairing an integrated care system or sustainability and transformation partnership. "Under current plans all parts...
Source: kingsfund.org.uk
Effect of alcohol on promise making - a prisoner
An Economic Analysis of Business Drinking: Evidence from a Lab-in-the-field Experiment
“Our GAAM (guilt aversion and alcohol myopia) model predicts that intoxication increases promise-making but has no effect on promise-breaking. We test these predictions using a prisoner’s dilemma game with pre-play...
Source: gmu.edu
Dying with smartphones - the anthropology of our relationship with machines.
'Dying with smartphones' by Daniel Miller "The hospice movement has grown up respecting that most people want to die in their own homes, even when they are living alone. But where is that home?" "We have witnessed how smartphones are becoming part of us, rather than simply something we use. Humanity...
Source: wordpress.com
Why People Demanded Privacy to Confide in the World
"To encourage ongoing dialogue, Weizenbaum designed Eliza to simulate the type of conversational style used by a Rogerian psychoanalyst. The program would take something the user said and reflect it back with a question
... during their brief interactions with Eliza, many users began forming emotional...
Source: ieee.org
Micro-credientials - the toy model and other perspectives.
25 Years of EdTech: 2019 – Micro-credentials.
"... micro-credentials represent the latest chapter in the attempt to make the shape of higher education more amorphous and flexible. In this, I am in favour of them, because if you want education to be inclusive and diverse then it needs to come in...
Source: edtechie.net
The Distinctions Between Theory, Theoretical Framework, and Conceptual Framework
"Health professions education (HPE) researchers are regularly asked to articulate their use of theory, theoretical frameworks, and conceptual frameworks in their research. However, all too often, these words are used interchangeably or without a clear understanding of the differences between these concepts....
Source: lww.com
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