Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound,
Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound, injected in to CSF and designed to reduce the production of all forms of the huntingtin (HTT) protein, which in its mutated variant (mHTT) is responsible for Huntington's Disease....
Source: reuters.com
Meta‐analysis of the procedural risks of carotid endarterectomy and carotid artery stenting over time: Stroke/death rates
Meta‐analysis of the procedural risks of carotid endarterectomy and carotid artery stenting over time: Stroke/death rates within 30 days of carotid endarterectomy (CEA) and carotid artery stenting (CAS) in RCTs inform current clinical guidelines. However, the risks may have changed in recent years...
Source: wiley.com
Association Between Treatment by Locum Tenens Internal Medicine Physicians and 30-Day Mortality Among Hospitalized Medicare
Association Between Treatment by Locum Tenens Internal Medicine Physicians and 30-Day Mortality Among Hospitalized Medicare Beneficiaries: This cohort study evaluates the differences in quality and costs of care related to locum tenens vs non–locum tenens physicians treating hospitalized Medicare beneficiaries....
Source: jamanetwork.com
What to Do When a Patient Has a 'Do Not Resuscitate' Tattoo: “We’ve always joked about this, but holy crap, this man
What to Do When a Patient Has a 'Do Not Resuscitate' Tattoo: “We’ve always joked about this, but holy crap, this man actually did it.” This is a good account in The Atlantic and highlights the ethical debate about consent. Many doctor and medico-legal comments have been circulating on social media...
Source: theatlantic.com
After 37 years, Voyager 1 has fired up its trajectory thrusters: This week, the scientists and engineers on the Voyager
After 37 years, Voyager 1 has fired up its trajectory thrusters: This week, the scientists and engineers on the Voyager team did something very special. What does this mean for Voyager and what effect will this thrust have on its trajectory? Great that the rockets work - fantastic engineering - and...
Source: arstechnica.com
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis: Objective To compare the efficacy, safety, and cost effectiveness of direct acting oral anticoagulants (DOACs) for patients with atrial fibrillation.
Design...
Source: bmj.com
Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study
Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study combined themes in cardiovascular modelling, clinical cardiology and e-learning to create an on-line environment that would assist undergraduate medical students in understanding...
Source: biomedcentral.com
A stable plasma ring has been created in open air for the first time ever: Researchers say it's "essentially capturing lightning
A stable plasma ring has been created in open air for the first time ever: Researchers say it's "essentially capturing lightning in a bottle, but without the bottle."
Source: futurism.com
A cross-sectional examination of psychological distress, positive mental health and their predictors in medical students
A cross-sectional examination of psychological distress, positive mental health and their predictors in medical students in their clinical clerkships: Medical students can experience the transition from theory to clinical clerkships as stressful. Scientific literature on the mental health of clinical...
Source: biomedcentral.com
Linking primary schools and care homes with letter writing pen pals. A great initiative that helps language skills and creative
Linking primary schools and care homes with letter writing pen pals. A great initiative that helps language skills and creative writing for children whilst also enabling otherwise isolated elders share memories and make new friends. I heard this story first on the radio with great examples of the types...
Source: bbc.co.uk
Towards a Competence-Based Course Authoring Tool Supporting Learning Management Systems: To establish a more comparable,
Towards a Competence-Based Course Authoring Tool Supporting Learning Management Systems: To establish a more comparable, compatible, and coherent system of higher education in Europe, the so-called Bologna Process (BP) has been adopted. As a measure to improve comparability, the BP requires that every...
Source: online-journals.org
A model for the use of blended learning in large group teaching sessions: Although blended learning has the potential to
A model for the use of blended learning in large group teaching sessions: Although blended learning has the potential to enhance the student experience, both in terms of engagement and flexibility, it can be difficult to effectively restructure existing courses. To achieve these goals for an introductory...
Source: biomedcentral.com
Using social media to support small group learning: Medical curricula are increasingly using small group learning and less
Using social media to support small group learning: Medical curricula are increasingly using small group learning and less didactic lecture-based teaching. This creates new challenges and opportunities in how students are best supported with information technology. We explored how university-supported...
Source: biomedcentral.com
The DPCC-MS communication skills competency instrument. A simple 5 item instrument. "Validation of the 5-item doctor-patient
The DPCC-MS communication skills competency instrument. A simple 5 item instrument. "Validation of the 5-item doctor-patient communication competency instrument for medical students (DPCC-MS) using two years of assessment data: Medical students on clinical rotations have to be assessed on several competencies...
Source: biomedcentral.com
Could analysing personalised learning be better matched if physicians are first classified into competency groups? Using
Could analysing personalised learning be better matched if physicians are first classified into competency groups? Using latent class analysis to identify physician competency reveals four distinct subgroups in this cross-sectional study in China. The survey tool is large at over 100 items long but included...
Source: biomedcentral.com
What do Japanese residents learn from treating dying patients? The implications for training in end-of-life care: How medical
What do Japanese residents learn from treating dying patients? The implications for training in end-of-life care: How medical residents’ experiences with care for dying patients affect their emotional well-being, their learning outcomes, and the formation of their professional identities is not fully...
Source: biomedcentral.com
The Health and Social Care Act of 2012 - making GPs lead Clinical Commissioning Groups - did not reduce overall hospitalisations
The Health and Social Care Act of 2012 - making GPs lead Clinical Commissioning Groups - did not reduce overall hospitalisations study concludes. "[G]iving control of healthcare budgets to GP-led CCGs was not associated
with a reduction in overall hospitalisations and was associated with an
increase...
Source: plos.org
Jarisch-Herxheimer and Lyme disease: When patients diagnosed with chronic Lyme are treated, no matter what happens as a
Jarisch-Herxheimer and Lyme disease: When patients diagnosed with chronic Lyme are treated, no matter what happens as a response to the treatment is considered by believers to be evidence in support of the diagnosis. If they get bette…
Source: sciencebasedmedicine.org
Reducing patient mortality, length of stay and readmissions through machine learning-based sepsis prediction in the emergency
Reducing patient mortality, length of stay and readmissions through machine learning-based sepsis prediction in the emergency department, intensive care unit and hospital floor units. Sepsis management is a challenge for hospitals nationwide, as severe sepsis carries high mortality rates and costs...
Source: bmj.com
The Red Roads to Timbuktu : Image of the Day: Iron-rich laterite give the roads to this remote city in central Mali a distinctive
The Red Roads to Timbuktu : Image of the Day: Iron-rich laterite give the roads to this remote city in central Mali a distinctive color.
Source: nasa.gov
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