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showing posts for 'trials'

Sudden Death Rates Drop in Trial Participants with Heart Failure: By Amy Orciari Herman Edited by Susan Sadoughi, MD,

Sudden Death Rates Drop in Trial Participants with Heart Failure: By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Rates of sudden death in patients with heart failure declined significantly over the past two decades, finds a study in the New England...
Source: jwatch.org

Diagnosis and management of dementia with Lewy bodies

"The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between clinical features...
Source: neurology.org

Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis

Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis of screening tests and interventions: Objectives  To assess diagnostic accuracy of screening tests for pre-diabetes and efficacy of interventions (lifestyle or metformin) in...
Source: bmj.com

OpenTrials API information: Since our beta launch last week, we’ve had a steady stream of technical questions about how

OpenTrials API information: Since our beta launch last week, we’ve had a steady stream of technical questions about how to use and interact with the data that powers OpenTrials. Good news! Right now we have a public API avail…
Source: opentrials.net

Good read. The most good you can do by Peter Singer. This is about effective altruism. If you are going to give away your

Good read. The most good you can do by Peter Singer. This is about effective altruism. If you are going to give away your money how can ensure you give it to the most effective resources? More than that if you've decided to give away money what is the best job that you can do? There are some extreme...
Source: amazon.co.uk

Corticosteroids for Bell's palsy | Cochrane "The available moderate- to high-quality evidence from randomised controlled

Corticosteroids for Bell's palsy | Cochrane "The available moderate- to high-quality evidence from randomised controlled trials showed significant benefit from treating Bell's palsy with corticosteroids. We calculated that to stop one person from being left with facial weakness, 10 people need to be...
Source: cochrane.org

To RCT or not to RCT? The ongoing saga of randomised trials in quality improvement Gareth Parry. Maxine Power. BMJ Quality

To RCT or not to RCT? The ongoing saga of randomised trials in quality improvement Gareth Parry. Maxine Power. BMJ Quality & Safety.
Source: bmj.com

First drug to reverse Huntington's disease begins human trials : The new drug, called IONIS-HTTRx, silences the gene known

First drug to reverse Huntington's disease begins human trials : The new drug, called IONIS-HTTRx, silences the gene known to be responsible for the production of a protein which causes Huntington’s
Source: telegraph.co.uk

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey Lars G Hemkens. Despina G Contopoulos-Ioannidis. John P A Ioannidis. BMJ.
Source: bmj.com

Can smartphone drug trials improve medical care?: A new clinical trial is attempting to track how participants suffering

Can smartphone drug trials improve medical care?: A new clinical trial is attempting to track how participants suffering from depression respond to mental health apps
Source: theguardian.com

Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors: In a joint publication

Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors: In a joint publication across 14 member journals, the International Committee of Medical Journal Editors (ICMJE) proposes to require sharing of deidentified individual patient data underlying published...
Source: plos.org

Lowering Blood Pressure Associated with Reductions in Cardiovascular Events, Meta-Analysis Finds: By Kelly Young Edited

Lowering Blood Pressure Associated with Reductions in Cardiovascular Events, Meta-Analysis Finds: By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH Reducing systolic blood pressure is associated with lower risk for cardiovascular events, suggests a meta-analysis in the Lancet...
Source: jwatch.org

Nearly 77 percent of pulmonary clinical trials failed to report race and ethnicity data: Researchers from Duke University

Nearly 77 percent of pulmonary clinical trials failed to report race and ethnicity data: Researchers from Duke University and Durham Veteran Affairs Medical Center have found that nearly 77 percent of pulmonary clinical trials registered with ClinicalTrials.gov failed to report race and ethnicity data,...
Source: eurekalert.org

Gene therapy staves off blindness from retinitis pigmentosa in canine model: Gene therapy preserved vision in a study involving

Gene therapy staves off blindness from retinitis pigmentosa in canine model: Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute, part of the National Institutes of Health. The findings...
Source: eurekalert.org

Gliptins and Cardiovascular Outcomes: A Comparative and Critical Analysis after TECOS: The issue related to macrovascular

Gliptins and Cardiovascular Outcomes: A Comparative and Critical Analysis after TECOS: The issue related to macrovascular outcomes and intensive glycemic control was hotly debated after the publication of landmark trials like ACCORD, ADVANCE, and VADT. The only benefits seem to come from intervening...
Source: hindawi.com