Milasen - a drug developed for a single patient.
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study.
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study. Designing learning for person-centred care is challenging and needs to involve an approach that works with HCPs and interdisciplinary teams. “With increasing numbers of people in the UK...
Source: biomedcentral.com
Training medical students to manage difficult circumstances- a curriculum for resilience and resourcefulness?: In response
Training medical students to manage difficult circumstances- a curriculum for resilience and resourcefulness?: In response to the growing prevalence of physical and emotional burnout amongst medical students and practicing physicians, we sought to find a new methodology to scope a five-year undergraduate...
Source: biomedcentral.com
Ebola outbreak in the Democratic Republic of the Congo declared a Public Health Emergency of International Concern: WHO
Ebola outbreak in the Democratic Republic of the Congo declared a Public Health Emergency of International Concern: WHO Director-General Dr. Tedros Adhanom Ghebreyesus today declared the Ebola virus disease (EVD) outbreak in the Democratic Republic of the Congo (DRC) a Public Health Emergency of International...
Source: who.int
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’ style payment model to incentivise pharmaceutical companies to develop new drugs for resistant infections.
"The new trial will be led by the National Institute for...
Source: www.gov.uk
The challenge of measuring real world community-based interventions. Exposure to a multi-level multi-component childhood
The challenge of measuring real world community-based interventions. Exposure to a multi-level multi-component childhood obesity prevention community-randomized controlled trial: patterns, determinants, and implications. - PubMed - NCB "Treatment effects may be attenuated in community-based trials,...
Source: nih.gov
WHO releases new International Classification of Diseases (ICD 11)
WHO releases new International Classification of Diseases (ICD 11)
Source: who.int
Greenland ice cores track Roman lead pollution in year-by-year detail: Studying the ice cores may help reconstruct fluctuations
Greenland ice cores track Roman lead pollution in year-by-year detail: Studying the ice cores may help reconstruct fluctuations in the ancient economy.
Source: arstechnica.com
Identifying low test-taking effort during low-stakes tests with the new Test-taking Effort Short Scale (TESS) - development
Identifying low test-taking effort during low-stakes tests with the new Test-taking Effort Short Scale (TESS) - development and psychometrics: "Low-stakes tests are becoming increasingly important in international assessments of educational progress, and the validity of these results is essential especially...
Source: biomedcentral.com
Reducing patient mortality, length of stay and readmissions through machine learning-based sepsis prediction in the emergency
Reducing patient mortality, length of stay and readmissions through machine learning-based sepsis prediction in the emergency department, intensive care unit and hospital floor units. Sepsis management is a challenge for hospitals nationwide, as severe sepsis carries high mortality rates and costs...
Source: bmj.com
Coming back from the edge: a qualitative study of a professional support unit for junior doctors: It is known that many
Coming back from the edge: a qualitative study of a professional support unit for junior doctors: It is known that many trainee doctors around the world experience work satisfaction but also considerable work stress in the training period. Such stress seems to be linked to multiple factors including...
Source: biomedcentral.com
Using a videogame to facilitate nursing and medical students' first visit to the operating theatre. A randomized controlled
Using a videogame to facilitate nursing and medical students' first visit to the operating theatre. A randomized controlled trial. - PubMed - NCBI
"A videogame was developed, combining pictures and short videos, by which students are interactively instructed on acting at the surgical block. Moreover,...
Source: nih.gov
RCEM calls for 2200 extra consultants as part of new strategy to help deliver better care in emergency departments. "The
RCEM calls for 2200 extra consultants as part of new strategy to help deliver better care in emergency departments. "The extra consultants are one of a range of measures detailed in the RCEM Vision 2020 – the College’s strategy to fix the problems facing emergency medicine in England." Being the...
Source: rcem.ac.uk
Passing the MRCP - an approach to REALLY hard questions. In your revision for the MRCP you will come across very tricky
Passing the MRCP - an approach to REALLY hard questions. In your revision for the MRCP you will come across very tricky MCQs. You know the ones ... the ones that you have no idea what the correct answer is, or the correct answer surprises you, or they are discussed by other candidates who can't agree...
Soft Robotic Exosuit Can Help Stroke Patients: Improvements seen within minutes of powering up the device. "Walsh and his
Soft Robotic Exosuit Can Help Stroke Patients: Improvements seen within minutes of powering up the device. "Walsh and his colleagues sought to develop a flexible lightweight wearable robot to support a weakened leg's residual ability to move. “By providing a small amount of assistance, our soft exosuit...
Source: ieee.org
Calorie restriction diet extends life of monkeys by years: Macaques on permanent diets live significantly longer – the
Calorie restriction diet extends life of monkeys by years: Macaques on permanent diets live significantly longer – the equivalent of nine years in people. But is the detailed meal planning and loss of libido worth it?
Source: newscientist.com
Baby dinosaur tail found preserved in amber, complete with feathers - ExtremeTech: Still have a hard time accepting dinosaurs
Baby dinosaur tail found preserved in amber, complete with feathers - ExtremeTech: Still have a hard time accepting dinosaurs had feathers? Here are some preserved in amber.
Source: extremetech.com
The Simple Economics of Machine Intelligence. Technological revolutions tend to involve some important activity becoming
The Simple Economics of Machine Intelligence. Technological revolutions tend to involve some important activity becoming cheap, like the cost of communication or finding information. Machine intelligence is, in its essence, a prediction technology, so the economic shift will center around a drop in the...
Source: digitopoly.org
Jam tomorrow: The meaning of non-tariff trade barriers - John Kay: The reality of Brexit and trade negotiations is a review
Jam tomorrow: The meaning of non-tariff trade barriers - John Kay: The reality of Brexit and trade negotiations is a review of the rules governing myriads of individual products in mind-numbing detail. Those who thought Brexit meant less regulation, less bureaucracy, fewer civil servants, are in for...
Source: johnkay.com
RSS feed