Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16%...
Source: nature.com
Biopharma futures
I've been looking at a few industry reports on the future of biopharma as part of a course I'm on with INSEAD Business School on Business Strategy and Financial Performance. I thought I'd share some of my ramblings on Biopharma Futures. Expectations are high Pharmaceutical
companies are operating...
Source: deanjenkins.me
6 expert essays on the future of biotech
How will biotechnology transform our approach to human health? Scientists from the World Economic Forum's Global Future Council share key insights. World Economic Forum future of biotech DNA technology - genetic screening for disease, recombinant protein production, CAR T cells, gene therapy, organoid...
Source: weforum.org
The future of biopharma
Shifts in how diseases are diagnosed and prevented, custom treatments, curative therapies, digital therapeutics, and precision intervention could upend current business models in biopharma. Deloitte's Five forces to 2040 Prevention and early detection Customized treatments - interventions for very...
Source: deloitte.com
Morgan Stanley: Global oil supply likely to peak earlier than demand
"Global oil supply is likely to peak even earlier than demand, Morgan Stanley said in a research note, based on its analysis on current trends." What does this mean? Investment in new oil and gas is falling because of policies to phase it out. This means the supply of fossil fuels will peak (or has peaked)...
Access to Medicines - inequalities persist but solutions must be found in partnership
Source: efpia.eu
Fatalism - the stalemate of us vs. COVID-19
Stephen Casper - medical historian at Clarkson University - offers a worrying prediction for COVID for the end of 2022. The analogy for COVID-19 won't be influenza but 'tuberculosis before the discovery of antibiotics'. A new hospital specialty might even exist - looking after COVID patients - and they...
Source: twitter.com
Factors affecting the uptake of new medicines: a systematic literature review - BMC Health Services Research Lublóy, Ágnes.
"This systematic literature review has provided insights into the factors that affect new drug uptake—primarily, doctors’ scientific orientation, prescribing habits, exposure to pharmaceutical marketing, and interpersonal communication." "Background The successful diffusion of new drugs is crucial...
Source: biomedcentral.com
Overturning 'conventional wisdom' with 'natural experiments'
Via Reuters ... "Economists David Card, Joshua Angrist and Guido Imbens won the 2021 Nobel economics prize on Monday for pioneering "natural experiments" to show real-world economic impacts in areas from minimum wage increases in the U.S. fast-food sector to migration from Castro-era Cuba." "One experiment...
Source: reuters.com
New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution
"Air pollution is one of the biggest environmental threats to human health, alongside climate change. New guidelines provide clear evidence of the damage air pollution inflicts on human health, at even lower concentrations than previously understood." "Global assessments of ambient air pollution alone...
Source: who.int
The Impact of Mask Distribution and Promotion on Mask Uptake and COVID-19 in Bangladesh
A growing body of scientific evidence suggests that face masks can protect against COVID-19. There is, however, limited rigorous evidence on the extent to which mask-wearing is effective in reducing COVID-19 in a real-life situation with imperfect and inconsistent mask use. In Bangladesh, researchers...
Source: poverty-action.org
Council policies 'inconsistent' with climate goals
A third of English councils support policies that could increase emissions, BBC research suggests.
Source: bbc.com
OpenAI's Codex Translates Everyday Language Into Computer Code
The company believes its Codex machine learning algorithm is the next step in programming—a sidekick for coders to speed up the work and ease the drudgery.
Source: singularityhub.com
The pandemic slashed the West Coast’s emissions. Wildfires already reversed it.
Major fires and resulting emissions are set to continually increase across the world’s forested regions, fueling more warming and more fires to come.
Source: technologyreview.com
Can Money Buy Happiness? A Review of New Data
Everyone knows the adage “money can’t buy happiness,” although few of us seem to believe it.
The best-known theory on this topic is that money actually can buy happiness, but only up to a point. This comes from a study by two Nobel Laureates, Daniel Kahneman and Angus Deaton (2010), which found...
Source: givingwhatwecan.org
Tailored messaging increases understanding of climate change in Republicans
A team of researchers at Yale University's Yale Program on Climate Change Communication has found that the use of tailored advertising can increase awareness among Republicans of the dangers posed by climate change. In their paper published in the journal Nature Climate Change, the group describes field...
Source: phys.org
China’s GPT-3? BAAI Introduces Superscale Intelligence Model ‘Wu Dao 1.0’ | Synced
The Beijing Academy of Artificial Intelligence (BAAI) releases Wu Dao 1.0, China’s first large-scale pretraining model.
Source: syncedreview.com
Alaska: Biden to suspend Trump Arctic drilling leases
The president will suspend oil and gas leases in Alaska's Arctic National Wildlife Refuge.
Source: bbc.com
Tracking SARS-CoV-2 variants
All viruses, including SARS-CoV-2, the virus that causes COVID-19, change over time. Most changes have little to no impact on the virus’ properties. However, some changes may affect the virus’s properties, such as how easily it spreads, the associated disease severity, or the performance...
Source: who.int
Greta Thunberg aims to change how food is produced
Swedish climate activist Greta Thunberg has set her sights on changing how the world produces and consumes food in order to counteract a trio of threats: carbon emissions, disease outbreaks and animal suffering.
Source: reuters.com
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