Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16%...
Source: nature.com
Biopharma 2020: A landmark year and a reset for the future
Biopharma in 2020 has shown what it can achieve when it works at its best. How can the industry build on this renewed sense of purpose in the years ahead? McKinsey biopharma 2020 3 Overarching trends Operating under a spotlight - expectation of innovationNavigating protracted economic uncertainty -...
Source: mckinsey.com
Internet user classification
Grampound it seems is classified as 'e-Rational Utilitarian' ... but who is shouting out for more local facilities and better internet infrastructure? Checks notes ... methodological individualist and political liberals with social stratification (i.e. class, status distinctions) playing a relatively...
Source: cdrc.ac.uk
Climate activists buy environment secretary's Cornwall constituency office
"Insulate Britain supporters donate rent from George Eustice MP's HQ towards protesters' court costs." Landlord activism.
Source: theguardian.com
The unhealthy industry playbook
What Public Health Practitioners Need to Know About Unhealthy IndustryTactics. Attack legitimate science. e.g. Accuse science of deception, calling it “junk science” or “bad science,” claiming science is manipulated to fulfill a political agenda. Attack and intimidate the scientists. e.g. Create...
Source: aphapublications.org
Early warnings and emerging accountability: Total's responses to global warming, 1971-2021 Global Environmental Change.
Building upon recent work on other major fossil fuel companies, we report new archival research and primary source interviews describing how Total responded to evolving climate science and policy in the last 50 years. We show that Total personnel received warnings of the potential for catastrophic global...
Source: sciencedirect.com
Meet the rogue birding group blocking wind energy at every turn
The American Bird Conservancy has repeatedly obstructed wind energy projects and become a go-to source for renewable energy opponents.
Source: grist.org
Psychology of panic buying
I've been fascinated by the psychology of panic buying and it is clearly an area for future research. It has an enormous impact on delivery infrastructure and I wonder if anyone has been tracking the data of the causes and the impact in the current fuel 'crisis'. A systematic review from last year identified...
Source: nih.gov
The Impact of Mask Distribution and Promotion on Mask Uptake and COVID-19 in Bangladesh
A growing body of scientific evidence suggests that face masks can protect against COVID-19. There is, however, limited rigorous evidence on the extent to which mask-wearing is effective in reducing COVID-19 in a real-life situation with imperfect and inconsistent mask use. In Bangladesh, researchers...
Source: poverty-action.org
Development and validation of teacher and student questionnaires measuring inhibitors of curriculum viability - BMC Medical
Background Curriculum viability is determined by the degree to which quality standards have or have not been met, and by the inhibitors that affect attainment of those standards. The literature reports many ways to evaluate whether a curriculum reaches its quality standards, but less attention is paid...
Source: biomedcentral.com
Council policies 'inconsistent' with climate goals
A third of English councils support policies that could increase emissions, BBC research suggests.
Source: bbc.com
New WHO toolkit promotes inclusion of people with dementia in society
“Towards a dementia-inclusive society: WHO toolkit for dementia-friendly initiatives”, launched today, is WHO’s latest response for establishing and scaling-up dementia-friendly initiatives globally. The toolkit helps countries raise public awareness and understanding of dementia to support people...
Source: who.int
Clinically contextualised ECG interpretation: the impact of prior clinical exposure and case vignettes on ECG diagnostic
Does teaching ECGs with a clinical vignette improve training? Not greatly ... but having seen a condition previously (and presumably the ECG that went with it) is probably best. The researchers concluded that "ECG training should therefore not rely on experiential learning
alone, but instead be supplemented...
Source: biomedcentral.com
Gout and 'Podagra' in medieval Cambridge, England - PubMed International journal of paleopathology.
"The high prevalence rate of gout in the friary is at least partly explained by the consumption of alcohol and purine-rich diets by the friars and the wealthy townsfolk. Medieval medical texts from Cambridge show that gout (known as podagra) was sometimes treated with medications made from the root of...
Source: nih.gov
Greta Thunberg aims to change how food is produced
Swedish climate activist Greta Thunberg has set her sights on changing how the world produces and consumes food in order to counteract a trio of threats: carbon emissions, disease outbreaks and animal suffering.
Source: reuters.com
The volunteers using 'honeypot' groups to fight anti-vax propaganda
Volunteers are busting anti-vaccine conspiracy theories with decoy Facebook groups.
Source: bbc.com
Constructing Transformers For Longer Sequences with Sparse Attention Methods
"We show that carefully designed sparse attention can be as expressive and flexible as the original full attention model. Along with theoretical guarantees, we provide a very efficient implementation which allows us to scale to much longer inputs. As a consequence, we achieve state-of-the-art results...
Source: googleblog.com
Effectiveness of a serious game addressing guideline adherence: cohort study with 1.5-year follow-up Tobias Raupach. Insa
Background Patients presenting with acute shortness of breath and chest pain should be managed according to guideline recommendations. Serious games can be used to train clinical reasoning. However, only few studies have used outcomes beyond student satisfaction, and most of the published evidence is...
Source: biomedcentral.com
Detection of a particle shower at the Glashow resonance with IceCube Nature.
The Glashow resonance describes the resonant formation of a W− boson during the interaction of a high-energy electron antineutrino with an electron1, peaking at an antineutrino energy of 6.3 petaelectronvolts (PeV) in the rest frame of the electron. Whereas this energy scale is out of reach for currently...
Source: nature.com
Medical educators’ beliefs about teaching, learning, and knowledge: development of a new framework
Interesting paper about beliefs among medical educators. This has been
developed with a qualitative study of undergraduate educators but the
framework makes for good reading for those of us involved in urging
colleagues and expert speakers to become more learner-centred. "The sharp divide between...
Source: biomedcentral.com
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