Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
After the morning after: what next for UK trade policy? - Trade Knowledge Exchange: In the aftermath of the UK General Elections, in which the Conservatives won 364 out of 650 seats in House of Commons, the question that arises is what this means for the UK and the EU. “Getting Brexit done” was,...
Source: trade-knowledge.net
Surgeons withdraw support for heart disease advice: European guidelines on a form of heart disease are under review, following a Newsnight investigation. “It is a matter of serious concern to us that some results in the Excel trial appear to have been concealed and that some patients may therefore...
Source: bbc.com
Animated video can more cost-effectively reach the widest – even
geographically isolated – populations, it readily complements extension
services and international development community efforts to secure
knowledge transfer and recipient buy-in for innovations. Implications
and future research...
Source: tandfonline.com
Would you pay $1 million to enroll in a phase 1 clinical trial of an “anti-aging” gene therapy? "Libella Gene Therapeutics, LLC made the news last week for announcing a “pay-to-play” trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it...
Source: sciencebasedmedicine.org
Video for learning is great at some things, not so great at others. Great summary of recent evidence from Donald Clark. What can we learn from Netflix? (Use technology appropriately not just the buzzwords) Episodic vs. Semantic memory (Remembering the right things from video isn't as easy as you think)...
Source: blogspot.com
A Promising Solar Energy Breakthrough Just Achieved 1,000-Degree Heat From Sunlight: A new startup backed by Bill Gates says it has managed to harness solar energy to greater effect than ever before, generating enough heat from a field of mirrored panels to drive the production of cement, steel and glass...
Source: sciencealert.com
Leading for integrated care: This report explores the progress, challenges and opportunities the move towards greater integration presents, through interviews with 16 people leading or chairing an integrated care system or sustainability and transformation partnership. "Under current plans all parts...
Source: kingsfund.org.uk
An Economic Analysis of Business Drinking: Evidence from a Lab-in-the-field Experiment
“Our GAAM (guilt aversion and alcohol myopia) model predicts that intoxication increases promise-making but has no effect on promise-breaking. We test these predictions using a prisoner’s dilemma game with pre-play...
Source: gmu.edu
"To encourage ongoing dialogue, Weizenbaum designed Eliza to simulate the type of conversational style used by a Rogerian psychoanalyst. The program would take something the user said and reflect it back with a question
... during their brief interactions with Eliza, many users began forming emotional...
Source: ieee.org
25 Years of EdTech: 2019 – Micro-credentials.
"... micro-credentials represent the latest chapter in the attempt to make the shape of higher education more amorphous and flexible. In this, I am in favour of them, because if you want education to be inclusive and diverse then it needs to come in...
Source: edtechie.net
"Health professions education (HPE) researchers are regularly asked to articulate their use of theory, theoretical frameworks, and conceptual frameworks in their research. However, all too often, these words are used interchangeably or without a clear understanding of the differences between these concepts....
Source: lww.com
Caring for doctors Caring for patients: An independent report into the wellbeing of UK medical students and doctors. "In 2018 we commissioned Professor Michael West and Dame Denise Coia, to carry out a UK-wide review to help tackle the causes of poor wellbeing faced by medical students and doctors.
...
Source: gmc-uk.org
"Two of the world’s biggest fund management bosses have called for a rethink of capitalism and its obsession with constant economic growth, in a plaintive appeal for business and governments to deal more decisively with the challenges of climate change.
Anne Richards, chief executive of Fidelity...
Source: www.ft.com
It marks the first time Pharmaceutical company Eisai has moved beyond medications and into digital health. The company’s Amazon Alexa skill – Ella the Jellyfish – has been developed for children with Lennox-Gastaut Syndrome (LGS) and was created with input from patients, their families and caregivers.
Source: epmmagazine.com
The Collective Journey is a way of explaining and retelling why something from the complex world has happened. Whilst it is a tool for storytellers to make compelling entertainment it also highlights the weakness of the single perspective in trying to understand the real world. “For centuries, every...
Source: collectivejourney.com
German Digital Healthcare Act - Frontiers Health: Bundestag adopts law on reimbursement for digital health application in Germany. "health apps, which can help patients to manage a diagnosed medical condition, can from January 2020 onwards be prescribed by their doctors. The costs are borne by the statutory...
Source: frontiers.health
Research suggests that, in certain cases, drones could quickly deliver life-saving interventions during city’s peak rush hour. Could drones be used someday to deliver life-saving medications or interventions in the case of a child’s emergency, a drug overdose or in response to a mass casualty scene?...
Source: aap.org
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study. Designing learning for person-centred care is challenging and needs to involve an approach that works with HCPs and interdisciplinary teams. “With increasing numbers of people in the UK...
Source: biomedcentral.com
Tick-borne encephalitis virus detected in ticks in the UK: Surveillance detects tick-borne encephalitis virus in 2 parts of England for the first time. "Tick-borne encephalitis virus (TBEV) has been detected for the first time in ticks in the UK. The findings are part of ongoing research by Public Health...
Source: www.gov.uk