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Drug therapy for delirium in terminally ill adults. Cochrane review.

Drug therapy for delirium in terminally ill adults. "terminally ill adults includes anyone with an advanced progressive illness such as advanced cancer, advanced dementia or organ failure, as well as those receiving hospice and end-of-life care ... " "We found low-quality evidence that, compared to...
Source: cochrane.org

WhatsApp: A Real-Time Tool to Reduce the Knowledge Gap and Share the Best Clinical Practices in Psoriasis

WhatsApp: A Real-Time Tool to Reduce the Knowledge Gap and Share the Best Clinical Practices in Psoriasis: Abstract Background: Psoriasis is a chronic inflammatory disease that affects around 100 million people worldwide. The burden of disease is high, but more recent therapies show promising results....
Source: liebertpub.com

New twist on marshmallow test: Kids depend on each other for self control

"New twist on marshmallow test: Kids depend on each other for self control: Simply placing kids in a cooperative environment boosts the ability to resist temptation. ... In the 1970s, the late psychologist Walter Mischel explored the importance of the ability to delay gratification as a child to one's...
Source: arstechnica.com

Diagnostic Tests for Syphilis Continue to Perplex Even the Experts

Diagnostic Tests for Syphilis Continue to Perplex Even the Experts: An Unanswerable Question in Infectious Diseases - HIV and ID Observations: Here’s a tricky clinical scenario: An elderly person with cognitive decline or some other non-specific neurologic symptom sees a clinician. Clinician sends...
Source: jwatch.org

Virtual reality technology for teaching neurosurgery of skull base tumor

Virtual reality technology for teaching neurosurgery of skull base tumor: Neurosurgery represents one of the most challenging and delicate of any surgical procedure. Skull base tumors in particular oftentimes present as a very technically difficult procedures in the setting of neurosurgical teaching....
Source: biomedcentral.com

The 100 Worst Ed-Tech Debacles of the Decade

The 100 Worst Ed-Tech Debacles of the Decade: "For the past ten years, I have written a lengthy year-end series, documenting some of the dominant narratives and trends in education technology. I think it is worthwhile, as the decade draws to a close, to review those stories and to see how much (or how...
Source: hackeducation.com

Moore's outcomes framework and related papers

blog post image Outcomes-based planning for CME (Continuing Medical Education) often cites Donald Moore, Professor of Medical Education at Vanderbilt University. In 2009 he published an outcomes framework for CME (1) - which expanded George Miller's 1990 competency pyramid (2) - followed by a more detailed explanation...
Source: agnate.co.uk

UCL cancer policy update

“Because of the complexity of delivering better cancer care and the dynamics of NHS funding and introducing better practices in the health service there is a strong case for developing new cancer strategies for all the UK nations for the 2020s. Britain could also benefit from leading an independent...
Source: ucl.ac.uk

In search of the secret handshakes of ID

"Many of my sponsoring stakeholders - that is, the people with the power to buy instructional design services - wouldn’t have known a learning solution if it bit them on the toe. Frankly, they really didn’t care about learning. They really didn’t want me to tell them...
Source: wixstatic.com

Media predictions for 2020 from BBC's Amol Rajan

Amol Rajan's 9 media predictions for 2020: Could we see streamageddon, eco-browsing, the break-up of Amazon and a new owner for ITV? "The data shows we really are living through the most extraordinarily peaceful, prosperous, wealthy, healthy, safe period in human history. There is strong evidence to...
Source: bbc.com

Dominic Cummings wants 'weirdos' to help run the UK. Will it work?: A senior adviser to the UK's prime minister suggests

Dominic Cummings wants 'weirdos' to help run the UK. Will it work?: A senior adviser to the UK's prime minister suggests policy-making can be improved by training AI on government data, but the researchers he cites say they aren't so sure
Source: newscientist.com

Earliest roasted root vegetables found in 170,000-year-old cave dirt: Charred fragments found in a cave in southern Africa

Earliest roasted root vegetables found in 170,000-year-old cave dirt: Charred fragments found in a cave in southern Africa suggest that the real “paleo diet” included lots of roasted root vegetables that were rich in carbohydrates
Source: newscientist.com

Mountain walker captures rare Brocken spectre: Rhys Pleming and his friend captured pictures of the rare weather phenomenon

Mountain walker captures rare Brocken spectre: Rhys Pleming and his friend captured pictures of the rare weather phenomenon on New Year's Day.
Source: bbc.com

Early warning signals for critical transitions in a thermoacoustic system:

Early warning signals for critical transitions in a thermoacoustic system: Dynamical systems can undergo critical transitions where the system suddenly shifts from one stable state to another at a critical threshold called the tipping point. The decrease in recovery rate to equilibrium (critical slowing...
Source: nature.com

Corporate bollox generator

blog post image Over the holiday season I have been fine-tuning a new improved "corporate bollox generator" which can now deliver whole sentences of management goop. Please feel free to give it a go. It is written in Javascript and generates random phrases by linking adverbs, verbs, adjectives, and nouns all selected...
Source: agnate.co.uk

Milasen - a drug developed for a single patient.

Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org

After the morning after: what next for UK trade policy? - Trade Knowledge Exchange: In the aftermath of the UK General Elections,

After the morning after: what next for UK trade policy? - Trade Knowledge Exchange: In the aftermath of the UK General Elections, in which the Conservatives won 364 out of 650 seats in House of Commons, the question that arises is what this means for the UK and the EU. “Getting Brexit done” was,...
Source: trade-knowledge.net

Cardiac guidelines challenged following investigation.

Surgeons withdraw support for heart disease advice: European guidelines on a form of heart disease are under review, following a Newsnight investigation. “It is a matter of serious concern to us that some results in the Excel trial appear to have been concealed and that some patients may therefore...
Source: bbc.com

Animated video can more cost-effectively reach the widest – even geographically isolated – populations, it readily

Animated video can more cost-effectively reach the widest – even geographically isolated – populations, it readily complements extension services and international development community efforts to secure knowledge transfer and recipient buy-in for innovations. Implications and future research...
Source: tandfonline.com

Would you pay $1 million to enroll in a phase 1 clinical trial of an

Would you pay $1 million to enroll in a phase 1 clinical trial of an “anti-aging” gene therapy? "Libella Gene Therapeutics, LLC made the news last week for announcing a “pay-to-play” trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it...
Source: sciencebasedmedicine.org