Milasen - a drug developed for a single patient.
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
People in Japan are wearing exoskeletons to keep working as they age: To solve the problem of Japan’s ageing workforce,
People in Japan are wearing exoskeletons to keep working as they age: To solve the problem of Japan’s ageing workforce, tech companies have developed exoskeletons that help older workers continue to do heavy manual labour
Source: newscientist.com
Would you pay $1 million to enroll in a phase 1 clinical trial of an
Would you pay $1 million to enroll in a phase 1 clinical trial of an “anti-aging” gene therapy? "Libella Gene Therapeutics, LLC made the news last week for announcing a “pay-to-play” trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it...
Source: sciencebasedmedicine.org
Yes you can learn surgery via YouTube
"Doctors are turning to YouTube to learn how to do surgical procedures, but there's no quality control: Tens of thousands of videos on YouTube show surgeries ranging from face-lifts to knee replacements. But the content isn't vetted or curated, and some doctors say it should be." The platform dominance...
Source: cnbc.com
HERhealth ... Increasing the ability of low-income women to take charge of their health
HERhealth™ | Programs | HERproject "Women working in global supply chains, many of whom are young and undereducated migrants, have limited health knowledge and often lack access to critical health services and products."
Source: herproject.org
Video for learning
Video for learning is great at some things, not so great at others. Great summary of recent evidence from Donald Clark. What can we learn from Netflix? (Use technology appropriately not just the buzzwords) Episodic vs. Semantic memory (Remembering the right things from video isn't as easy as you think)...
Source: blogspot.com
'If you think competition is hard, you should try collaboration.'
Leading for integrated care: This report explores the progress, challenges and opportunities the move towards greater integration presents, through interviews with 16 people leading or chairing an integrated care system or sustainability and transformation partnership. "Under current plans all parts...
Source: kingsfund.org.uk
Effect of alcohol on promise making - a prisoner
An Economic Analysis of Business Drinking: Evidence from a Lab-in-the-field Experiment
“Our GAAM (guilt aversion and alcohol myopia) model predicts that intoxication increases promise-making but has no effect on promise-breaking. We test these predictions using a prisoner’s dilemma game with pre-play...
Source: gmu.edu
The origin and meaning of a
Waterfall Process: A waterfall software process breaks down a large effort into a sequence of activities, usually leaving risks too late.
Source: martinfowler.com
Autonomy, Belonging, Competence. GMC reports on the ABC of wellbeing.
Caring for doctors Caring for patients: An independent report into the wellbeing of UK medical students and doctors. "In 2018 we commissioned Professor Michael West and Dame Denise Coia, to carry out a UK-wide review to help tackle the causes of poor wellbeing faced by medical students and doctors.
...
Source: gmc-uk.org
City fund managers call for rethink of capitalism
"Two of the world’s biggest fund management bosses have called for a rethink of capitalism and its obsession with constant economic growth, in a plaintive appeal for business and governments to deal more decisively with the challenges of climate change.
Anne Richards, chief executive of Fidelity...
Source: www.ft.com
Eisai launches a digital health solution on Amazon Alexa for children with a rare form of epilepsy - Lennox-Gastaut Syndrome.
It marks the first time Pharmaceutical company Eisai has moved beyond medications and into digital health. The company’s Amazon Alexa skill – Ella the Jellyfish – has been developed for children with Lennox-Gastaut Syndrome (LGS) and was created with input from patients, their families and caregivers.
Source: epmmagazine.com
AI helps to improve radiologist performance.
In a multicenter study, radiologists had better performance with deep convolutional network software for the detection of malignant pulmonary nodules on chest radiographs than without. Deep Convolutional Neural Network-based Software Improves Radiologist Detection of Malignant Lung Nodules on Chest Radiographs....
Source: rsna.org
5 Features of Modern Workplace Learning
"5 Features of Modern Workplace Learning - Modern Workplace Learning 2020: There is a big mismatch between how individuals acquire new knowledge and skills and what they value (discovery, discourse and doing), and what organisations focus on and value (didactics). Modern Workplace Learning (MWL) is an...
Source: modernworkplacelearning.com
14 Different Types of Learning in Machine Learning.
14 Different Types of Learning in Machine Learning: Machine learning is a large field of study that overlaps with and inherits ideas from many related fields such as artificial intelligence. The focus of the field is learning, that is, acquiring skills or knowledge from experience. Most commonly, this...
Source: machinelearningmastery.com
Open is Eating the World: What Source Code and Science Have in Common.
"Open is Eating the World: What Source Code and Science Have in Common: In 2011, Marc Andreessen said that software is eating the world, predicting that technology companies would continue to significantly disrupt an increasingly broad range of industries. Since then, publishers have embraced technology....
Source: sspnet.org
After Spike in Deaths, New York to Get 250 Miles of Protected Bike Lanes.
After Spike in Deaths, New York to Get 250 Miles of Protected Bike Lanes: The city will build the lanes as part of a $1.7 billion street safety plan to be adopted by Mayor Bill de Blasio and the City Council.
Source: nytimes.com
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study.
Factors associated with successful dementia education for practitioners in primary care: an in-depth case study. Designing learning for person-centred care is challenging and needs to involve an approach that works with HCPs and interdisciplinary teams. “With increasing numbers of people in the UK...
Source: biomedcentral.com
Teaching a difficult topic in medical genetics using a problem-based concept resembling a computer game.
Teaching a difficult topic using a problem-based concept resembling a computer game: development and evaluation of an e-learning application for medical molecular genetics: E-learning through serious gaming. Teaching concepts such as genetic testing and the digital literacy required to analyse data can...
Source: biomedcentral.com
Physicians reported less burnout and emotional exhaustion after receiving short-term professional coaching.
Physicians reported less burnout and emotional exhaustion after receiving short-term professional coaching, according to a pilot trial published in JAMA Internal Medicine. Counseling Reduces Physician Burnout Anita Slomski. JAMA. 2019;322(16):1544 This editorial in JAMA comments on the recent paper:...
Source: jamanetwork.com
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